HitPredict

Interactor 1: TSN3 (O60637)
Tetraspanin-3 (Tspan-3) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8)
Gene: TSPAN3

Interactor 2: TSN15 (O95858)
Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane 4 superfamily member 15)
Gene: TSPAN15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 253 Hs			1 294
+	Hs
		349393 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		TSN15_HUMAN (1-294): 2.67e-95: 284: 100.00
+	Hs
		349402 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		TSN15_HUMAN (1-294): 2.67e-95: 284: 100.00
+	Hs
		298985 TSN9_HUMAN (1-240): 1.47e-61: 195: 24.58		TSN15_HUMAN (1-294): 2.67e-95: 284: 100.00
+	Hs
		873784 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		TSN14_HUMAN (9-268): 1.08e-76: 236: 31.46
+	Hs
		967327 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		TSN14_HUMAN (9-268): 1.08e-76: 236: 31.46
+	Hs
		252650 TSN3_HUMAN (1-253): 1.8e-66: 208: 100.00		CD63_HUMAN (11-261): 6.06e-59: 189: 23.81
+	Hs
		873767 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		CD151_HUMAN (13-264): 1.97e-58: 189: 22.96
+	Hs
		298987 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		TSN9_HUMAN (13-266): 8.75e-58: 187: 23.64
+	Hs
		697351 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		CD82_HUMAN (13-264): 1.6e-56: 184: 17.80
+	Hs
		477405 CD82_HUMAN (1-243): 1.28e-58: 188: 26.72		CD63_HUMAN (11-261): 6.06e-59: 189: 23.81
+	Hs
		641923 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		CD9_HUMAN (11-263): 2.65e-52: 172: 15.33
+	Hs
		641933 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		CD9_HUMAN (11-263): 2.65e-52: 172: 15.33
+	Hs
		873766 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		CD81_HUMAN (11-262): 3.86e-52: 172: 15.53
+	Hs
		948746 TSN5_HUMAN (6-238): 1.45e-61: 196: 20.95		CD81_HUMAN (11-262): 3.86e-52: 172: 15.53
+	Hs
		298986 TSN9_HUMAN (1-240): 1.47e-61: 195: 24.58		CD9_HUMAN (11-263): 2.65e-52: 172: 15.33
+	Hs
		641915 CD82_HUMAN (1-243): 1.28e-58: 188: 26.72		CD9_HUMAN (11-263): 2.65e-52: 172: 15.33
+	Hs
		873787 CD151_HUMAN (3-238): 7.87e-62: 196: 26.97		TSN18_HUMAN (16-260): 1.18e-47: 161: 18.47
+	Hs
		622031 CD82_HUMAN (1-243): 1.28e-58: 188: 26.72		CD53_HUMAN (16-260): 7.47e-48: 161: 19.92