HitPredict

Interactor 1: TSN3 (O60637)
Tetraspanin-3 (Tspan-3) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8)
Gene: TSPAN3

Interactor 2: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 253 Hs			1 822
+	Hs
		252658 TSN3_HUMAN (1-253): 1.8e-66: 208: 100.00		FGFR2_HUMAN (1-812): 0: 794: 71.50
+	Hs
		252670 TSN3_HUMAN (1-253): 1.8e-66: 208: 100.00		EPHA5_HUMAN (3-791): 0: 630: 18.90
+	Hs
		252671 TSN3_HUMAN (1-253): 1.8e-66: 208: 100.00		EPHA4_HUMAN (3-783): 0: 615: 19.44
+	Hs
		349381 TSN15_HUMAN (9-238): 1.91e-50: 168: 20.82		EPHB2_HUMAN (4-819): 0: 637: 18.07
+	Hs
		349623 TSN12_HUMAN (5-233): 2.48e-48: 163: 21.72		EPHA2_HUMAN (3-819): 0: 583: 18.48
+	Hs
		931925 CD81_HUMAN (4-243): 1.42e-52: 172: 18.95		EPHB4_HUMAN (3-777): 2.29e-177: 538: 17.74