HitPredict

Interactor 1: MCM7 (O75001)
DNA replication licensing factor mcm7 (EC 3.6.4.12) (Minichromosome maintenance protein 7)
Gene: MCM7

Interactor 2: MCM6 (P49731)
DNA replication licensing factor mcm6 (EC 3.6.4.12) (Minichromosome maintenance protein 6)
Gene: MCM6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 11606526, 9705352, 10770926, 21813639, 11136247, 23444842
Identification Methods affinity chromatography technology, biochemical, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM6_C, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM6_C~MCM_lid, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0000785 - chromatin
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 760
Sp

1 892
+ Hs
+ Xl
+ At
+ Sc
+ Dm
+ Sp
+ Xl
+ Hs
+ Hs
+ Xl
+ Xl
+ Xl
+ Hs
+ Dm
+ Hs
+ Mm
+ Dm
+ Sc
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024