HitPredict

Interactor 1: IGSF3 (O75054)
Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3)
Gene: IGSF3

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.595

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~V-set
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1194 Hs			1 126
+	Hs
		253633 IGSF3_HUMAN (1-1194): 0: 758: 100.00		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		1129835 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		617967 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21
+	Hs
		1274395 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		1281777 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1M_HUMAN (1-126): 5.38e-54: 166: 96.03
+	Hs
		420868 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21
+	Hs
		918584 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		241603 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		707706 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		1281776 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1N_HUMAN (1-126): 3.35e-53: 164: 98.41
+	Hs
		886172 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		1281778 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		1281772 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Hs
		255826 OBSL1_HUMAN (569-1111): 5.19e-26: 118: 11.36		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		256017 OBSL1_HUMAN (569-1111): 5.19e-26: 118: 11.36		H2B1N_HUMAN (1-126): 3.35e-53: 164: 98.41
+	Hs
		1087182 OBSCN_HUMAN (59-438): 7.71e-12: 72.7: 12.76		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		617962 TITIN_HUMAN (8-138): 9.96e-10: 65.7: 13.24		H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21
+	Hs
		883041 TITIN_HUMAN (8-138): 9.96e-10: 65.7: 13.24		H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83
+	Hs
		241595 TITIN_HUMAN (8-138): 9.96e-10: 65.7: 13.24		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		886166 TITIN_HUMAN (8-138): 9.96e-10: 65.7: 13.24		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41