HitPredict

Interactor 1: IGSF3 (O75054)
Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3)
Gene: IGSF3

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 22268729
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1194 Hs			1 293
+	Hs
		253677 IGSF3_HUMAN (1-1194): 0: 758: 100.00		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		957565 PGBM_HUMAN (5-683): 2.83e-61: 233: 11.34		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1281788 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		957568 PGBM_HUMAN (5-683): 2.83e-61: 233: 11.34		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1344584 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1274004 IGSF2_HUMAN (1-418): 5.37e-28: 124: 16.16		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1018314 CNTN1_HUMAN (723-1176): 4.55e-24: 111: 11.09		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1123262 SDK2_HUMAN (583-1172): 1.81e-22: 107: 12.14		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1356264 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1350209 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17