HitPredict

Interactor 1: LPXN (O60711)
Leupaxin
Gene: LPXN

Interactor 2: LMO3 (Q8TAP4)
LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) (Rhombotin-3)
Gene: LMO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 386 Hs			1 145
+	Hs
		253936 LPXN_HUMAN (13-384): 3.43e-92: 283: 100.00		RBTN1_HUMAN (1-133): 4.57e-36: 123: 95.49
+	Hs
		681870 ZNF34_HUMAN (12-383): 2.93e-80: 258: 12.40		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Hs
		212715 TGFI1_HUMAN (1-385): 6.53e-86: 270: 44.44		PAXI_HUMAN (3-135): 5.26e-32: 120: 24.06
+	Hs
		253986 LPXN_HUMAN (13-384): 3.43e-92: 283: 100.00		PDLI7_HUMAN (70-145): 4.23e-15: 72.7: 23.68
+	Hs
		585009 ZN250_HUMAN (51-324): 1.33e-57: 198: 8.93		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Hs
		253972 LPXN_HUMAN (13-384): 3.43e-92: 283: 100.00		LPP_HUMAN (4-66): 2.34e-11: 61.9: 22.86
+	Hs
		681832 FHL5_HUMAN (175-385): 2.99e-55: 185: 25.58		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Ce
		113389 PXL1_CAEEL (15-386): 2.39e-77: 246: 35.22		G5EFL5_CAEEL (68-144): 7.91e-15: 71.9: 15.19
+	Hs
		681810 FHL3_HUMAN (123-320): 5.6e-43: 152: 27.45		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Hs
		965447 FHL3_HUMAN (123-320): 5.6e-43: 152: 27.45		LMO4_HUMAN (11-142): 2.91e-41: 137: 50.76
+	Dm
		1477952 Q9VVB5_DROME (113-385): 4.03e-61: 208: 24.30		Q9VJ00_DROME (75-144): 5.01e-11: 61.2: 21.43
+	Hs
		681820 ZYX_HUMAN (270-385): 1.67e-29: 121: 31.09		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Hs
		913832 ZN135_HUMAN (22-231): 3.56e-32: 129: 6.60		LMO4_HUMAN (11-142): 2.91e-41: 137: 50.76
+	Hs
		1216161 FHL5_HUMAN (175-385): 2.99e-55: 185: 25.58		PDLI7_HUMAN (70-145): 4.23e-15: 72.7: 23.68
+	Hs
		682012 PAXI_HUMAN (270-385): 1.81e-28: 118: 37.07		RBTN1_HUMAN (1-133): 4.57e-36: 123: 95.49
+	Hs
		878469 ZYX_HUMAN (270-385): 1.67e-29: 121: 31.09		PAXI_HUMAN (3-135): 5.26e-32: 120: 24.06
+	Hs
		322517 ABLM3_HUMAN (210-386): 3.48e-39: 150: 22.87		PDLI7_HUMAN (70-145): 4.23e-15: 72.7: 23.68
+	Hs
		1156226 ZYX_HUMAN (270-385): 1.67e-29: 121: 31.09		PDLI7_HUMAN (70-145): 4.23e-15: 72.7: 23.68
+	Hs
		1156179 ZYX_HUMAN (270-385): 1.67e-29: 121: 31.09		PDLI5_HUMAN (3-66): 1.23e-12: 65.8: 27.69
+	Hs
		1156172 ZYX_HUMAN (270-385): 1.67e-29: 121: 31.09		LPP_HUMAN (4-66): 2.34e-11: 61.9: 22.86