HitPredict

Interactor 1: RBTN1 (P25800)
Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM domain only protein 1) (LMO-1) (T-cell translocation protein 1)
Gene: LMO1

Interactor 2: PAXI (P49023)
Paxillin
Gene: PXN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 591
+	Hs
		878520 LMO3_HUMAN (13-156): 5.12e-39: 130: 89.58		PAXI_HUMAN (12-591): 1.66e-110: 344: 100.00
+	Hs
		681870 RBTN2_HUMAN (7-149): 3.38e-46: 149: 54.17		ZNF34_HUMAN (134-586): 2.46e-82: 270: 12.22
+	Hs
		1153645 LMO3_HUMAN (13-156): 5.12e-39: 130: 89.58		ZKSC8_HUMAN (119-526): 1.48e-66: 229: 10.70
+	Hs
		870147 LMO3_HUMAN (13-156): 5.12e-39: 130: 89.58		LIMS1_HUMAN (346-529): 3.49e-43: 159: 32.97
+	Hs
		212715 PAXI_HUMAN (85-152): 6.23e-13: 66.9: 24.64		TGFI1_HUMAN (71-532): 3.06e-63: 217: 25.96
+	Hs
		253936 RBTN1_HUMAN (1-156): 1.39e-43: 142: 100.00		LPXN_HUMAN (353-473): 6.37e-35: 137: 35.54
+	Ce
		113389 G5EFL5_CAEEL (2-77): 8.93e-17: 78.1: 23.08		PXL1_CAEEL (143-532): 1.8e-57: 200: 19.75
+	Hs
		253971 LMO3_HUMAN (13-156): 5.12e-39: 130: 89.58		LPXN_HUMAN (353-473): 6.37e-35: 137: 35.54
+	Hs
		681810 RBTN2_HUMAN (7-149): 3.38e-46: 149: 54.17		FHL3_HUMAN (351-467): 2.62e-27: 113: 32.23
+	Hs
		681832 RBTN2_HUMAN (7-149): 3.38e-46: 149: 54.17		FHL5_HUMAN (329-467): 2.87e-26: 110: 24.48
+	Hs
		681944 RBTN2_HUMAN (7-149): 3.38e-46: 149: 54.17		LIMD1_HUMAN (467-588): 1.4e-22: 104: 22.48
+	Hs
		1393046 PDLI5_HUMAN (20-153): 1.76e-31: 119: 26.12		PDLI7_HUMAN (61-467): 9.06e-33: 133: 16.71
+	Hs
		682014 RBTN1_HUMAN (1-156): 1.39e-43: 142: 100.00		ZNF84_HUMAN (81-355): 9.75e-24: 108: 8.96
+	Hs
		965447 LMO4_HUMAN (7-154): 2.54e-39: 132: 47.30		FHL3_HUMAN (351-467): 2.62e-27: 113: 32.23
+	Hs
		903055 LMO3_HUMAN (13-156): 5.12e-39: 130: 89.58		ZNF84_HUMAN (81-355): 9.75e-24: 108: 8.96
+	Hs
		870115 PAXI_HUMAN (85-152): 6.23e-13: 66.9: 24.64		LIMS1_HUMAN (346-529): 3.49e-43: 159: 32.97
+	Dm
		1477952 Q9VJ00_DROME (2-151): 2.07e-40: 143: 32.28		Q9VVB5_DROME (335-413): 5.6e-09: 61.1: 19.28
+	Hs
		159169 PAXI_HUMAN (85-152): 6.23e-13: 66.9: 24.64		ABLM1_HUMAN (274-452): 4.71e-29: 124: 26.11
+	Hs
		1393027 PDLI5_HUMAN (20-153): 1.76e-31: 119: 26.12		PDLI5_HUMAN (530-590): 5.35e-11: 67.2: 34.43
+	Ce
		113356 G5EFL5_CAEEL (2-77): 8.93e-17: 78.1: 23.08		G5EFL5_CAEEL (473-590): 1.14e-14: 79.7: 35.00