HitPredict

Interactor 1: RBTN2 (P25791)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: LMO2

Interactor 2: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 572
+	Hs
		1156179 PDLI5_HUMAN (2-154): 9.37e-35: 128: 23.23		ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00
+	Hs
		681944 RBTN2_HUMAN (1-158): 5.59e-42: 138: 100.00		LIMD1_HUMAN (1-571): 5.97e-65: 226: 22.80
+	Hs
		681818 RBTN2_HUMAN (1-158): 5.59e-42: 138: 100.00		TRIP6_HUMAN (63-571): 7.13e-66: 224: 32.82
+	Hs
		1347335 LMO3_HUMAN (30-156): 6.25e-39: 130: 58.27		FBLI1_HUMAN (252-572): 4.15e-67: 224: 29.61
+	Hs
		878469 PAXI_HUMAN (3-88): 1.4e-17: 80.4: 19.77		ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00
+	Ce
		628572 LIN11_CAEEL (30-153): 1.14e-20: 88.6: 34.40		ZYX_CAEEL (8-570): 1.18e-67: 232: 21.27
+	Hs
		878576 PAXI_HUMAN (3-88): 1.4e-17: 80.4: 19.77		LIMD1_HUMAN (1-571): 5.97e-65: 226: 22.80
+	Hs
		253936 RBTN1_HUMAN (20-150): 3.92e-39: 131: 55.73		LPXN_HUMAN (221-570): 4.44e-48: 174: 18.18
+	Hs
		878467 PAXI_HUMAN (3-88): 1.4e-17: 80.4: 19.77		TRIP6_HUMAN (63-571): 7.13e-66: 224: 32.82
+	Hs
		253971 LMO3_HUMAN (30-156): 6.25e-39: 130: 58.27		LPXN_HUMAN (221-570): 4.44e-48: 174: 18.18
+	Hs
		682012 RBTN1_HUMAN (20-150): 3.92e-39: 131: 55.73		PAXI_HUMAN (5-500): 2.09e-31: 130: 13.85
+	Hs
		878520 LMO3_HUMAN (30-156): 6.25e-39: 130: 58.27		PAXI_HUMAN (5-500): 2.09e-31: 130: 13.85
+	Ce
		113389 G5EFL5_CAEEL (2-83): 8.6e-18: 81.1: 19.28		PXL1_CAEEL (243-571): 2.22e-48: 175: 19.22
+	Hs
		1393027 PDLI5_HUMAN (2-154): 9.37e-35: 128: 23.23		PDLI5_HUMAN (115-572): 6.34e-30: 126: 16.67
+	Hs
		878412 PAXI_HUMAN (3-88): 1.4e-17: 80.4: 19.77		PAXI_HUMAN (5-500): 2.09e-31: 130: 13.85
+	Hs
		681810 RBTN2_HUMAN (1-158): 5.59e-42: 138: 100.00		FHL3_HUMAN (410-544): 1.64e-09: 61.2: 28.99
+	Hs
		870147 LMO3_HUMAN (30-156): 6.25e-39: 130: 58.27		LIMS1_HUMAN (383-566): 1.09e-10: 65.1: 25.95
+	Hs
		965447 LMO4_HUMAN (11-147): 1.13e-38: 130: 42.34		FHL3_HUMAN (410-544): 1.64e-09: 61.2: 28.99
+	Hs
		870115 PAXI_HUMAN (3-88): 1.4e-17: 80.4: 19.77		LIMS1_HUMAN (383-566): 1.09e-10: 65.1: 25.95
+	Hs
		212715 PAXI_HUMAN (3-88): 1.4e-17: 80.4: 19.77		TGFI1_HUMAN (377-441): 9.84e-10: 63: 32.31