HitPredict

Interactor 1: T22D2 (O75157)
TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4)
Gene: TSC22D2

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	27337956
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 780 Hs			1 342
+	Hs
		1309278 TARA_HUMAN (21-763): 1e-27: 123: 10.47		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		847067 SMCA4_HUMAN (270-730): 1.79e-25: 115: 12.33		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		725569 CHD8_HUMAN (163-779): 3.15e-26: 118: 11.96		COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38
+	Hs
		979963 IF4G1_HUMAN (220-770): 1.15e-25: 116: 13.76		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		847050 SMCA4_HUMAN (270-730): 1.79e-25: 115: 12.33		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		1281391 PRR36_HUMAN (1-680): 2.25e-18: 92.7: 11.39		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		725454 T22D1_HUMAN (7-764): 5.16e-10: 65.4: 16.14		COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38
+	Hs
		1281504 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		1309165 CHD8_HUMAN (163-779): 3.15e-26: 118: 11.96		TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38
+	Hs
		903535 CHD8_HUMAN (163-779): 3.15e-26: 118: 11.96		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		903152 IF4G1_HUMAN (220-770): 1.15e-25: 116: 13.76		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Dm
		248488 Q9VLS7_DROME (7-751): 1.79e-10: 66.9: 10.91		COPB2_DROME (22-239): 4.04e-34: 134: 15.70
+	Dm
		52831 A1Z813_DROME (240-568): 2.33e-09: 63.2: 17.76		EBI_DROME (161-342): 6.92e-30: 122: 15.98
+	Hs
		245651 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		TBL1X_HUMAN (162-342): 3.97e-28: 116: 15.46
+	Dm
		1370295 Q9VLS7_DROME (7-751): 1.79e-10: 66.9: 10.91		POC1_DROME (201-335): 1.71e-23: 101: 19.12
+	Hs
		1318191 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		TBL1R_HUMAN (206-337): 3.38e-19: 90.1: 13.01
+	Hs
		903374 KMT2C_HUMAN (2-535): 6.44e-09: 61.9: 9.98		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79