HitPredict

Interactor 1: T22D2 (O75157)
TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4)
Gene: TSC22D2

Interactor 2: NRBP2 (Q9NSY0)
Nuclear receptor-binding protein 2 (Transformation-related gene 16 protein) (TRG-16)
Gene: NRBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 780 Hs			1 501
+	Hs
		256836 T22D2_HUMAN (1-780): 4.53e-60: 219: 100.00		NRBP_HUMAN (2-500): 1.46e-121: 368: 59.36
+	Hs
		256827 T22D2_HUMAN (1-780): 4.53e-60: 219: 100.00		WNK3_HUMAN (29-469): 1.34e-107: 353: 24.62
+	Hs
		256834 T22D2_HUMAN (1-780): 4.53e-60: 219: 100.00		STK39_HUMAN (34-501): 3.81e-114: 349: 14.78
+	Hs
		1304682 T22D3_HUMAN (671-779): 3.32e-39: 143: 55.86		NRBP_HUMAN (2-500): 1.46e-121: 368: 59.36
+	Hs
		1304681 T22D3_HUMAN (671-779): 3.32e-39: 143: 55.86		NRBP2_HUMAN (28-501): 4.48e-120: 363: 100.00
+	Hs
		1186099 MICA3_HUMAN (232-778): 1.95e-24: 112: 15.51		AKT3_HUMAN (10-380): 1.73e-120: 363: 14.44
+	Hs
		847056 SMCA4_HUMAN (270-730): 1.79e-25: 115: 12.33		MARK4_HUMAN (9-494): 3.47e-114: 355: 13.62
+	Dm
		1098027 BUN2_DROME (674-760): 7.41e-15: 81.3: 59.55		NRBP_DROME (13-494): 3.82e-115: 355: 47.31
+	Hs
		1077357 T22D1_HUMAN (7-764): 5.16e-10: 65.4: 16.14		NRBP_HUMAN (2-500): 1.46e-121: 368: 59.36
+	Hs
		1355633 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		NRBP_HUMAN (2-500): 1.46e-121: 368: 59.36
+	Hs
		1077348 T22D1_HUMAN (7-764): 5.16e-10: 65.4: 16.14		NRBP2_HUMAN (28-501): 4.48e-120: 363: 100.00
+	Hs
		1345645 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		NRBP2_HUMAN (28-501): 4.48e-120: 363: 100.00
+	Rn
		914592 T22D1_RAT (6-777): 1.19e-09: 64.2: 11.40		AKT3_RAT (10-380): 8.84e-119: 359: 14.17
+	Hs
		1077338 T22D1_HUMAN (7-764): 5.16e-10: 65.4: 16.14		WNK1_HUMAN (5-314): 1.72e-107: 354: 29.48
+	Hs
		1330751 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		WNK1_HUMAN (5-314): 1.72e-107: 354: 29.48
+	Hs
		1317207 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		WNK3_HUMAN (29-469): 1.34e-107: 353: 24.62
+	Hs
		1354609 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		STK39_HUMAN (34-501): 3.81e-114: 349: 14.78
+	Hs
		871507 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		AAPK2_HUMAN (37-478): 4.84e-109: 336: 15.27
+	Hs
		1025245 T22D4_HUMAN (136-326): 2.16e-09: 62.4: 29.38		AAPK1_HUMAN (37-476): 4.17e-99: 311: 15.25
+	Hs
		979887 IF4G1_HUMAN (220-770): 1.15e-25: 116: 13.76		PAK2_HUMAN (4-317): 7.65e-70: 233: 22.85