HitPredict

Interactor 1: PP6R2 (O75170)
Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)
Gene: PPP6R2

Interactor 2: ASPM (Q8IZT6)
Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog)
Gene: ASPM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 966 Hs			1 3477
+	Hs
		257239 PP6R2_HUMAN (1-966): 0: 893: 100.00		MYO5A_HUMAN (1780-2618): 8.03e-28: 126: 10.43
+	Hs
		257225 PP6R2_HUMAN (1-966): 0: 893: 100.00		MYO5C_HUMAN (2658-3307): 6.45e-23: 110: 10.82
+	Hs
		257234 PP6R2_HUMAN (1-966): 0: 893: 100.00		MYO5B_HUMAN (1256-1945): 6.28e-14: 81.1: 13.87
+	Hs
		506823 HUWE1_HUMAN (487-954): 7.07e-26: 118: 13.22		SPTB1_HUMAN (929-2995): 1.76e-100: 365: 9.24
+	Hs
		513870 TENS2_HUMAN (596-922): 8.28e-17: 88.1: 13.15		DMD_HUMAN (1507-3476): 2.32e-27: 125: 7.73
+	Mm
		1143711 HUWE1_MOUSE (487-956): 1.3e-28: 126: 12.27		SPTB2_MOUSE (2326-3469): 2.02e-10: 69.4: 8.64