Interactor 1: LRP5 (O75197)
Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7)
Gene: LRP5

Interactor 2: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 28966723
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FXa_inhibition~FXa_inhibition, FXa_inhibition~Ldl_recept_a, FXa_inhibition~Ldl_recept_b, Ldl_recept_a~Ldl_recept_a, Ldl_recept_a~Ldl_recept_b, Ldl_recept_b~Ldl_recept_b
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0015026 - coreceptor activity
GO:0017147 - Wnt-protein binding
GO:0042813 - Wnt receptor activity
and 8 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1615
Hs

1 1613
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024