HitPredict

Interactor 1: CAD16 (O75309)
Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin)
Gene: CDH16

Interactor 2: PCDGB (Q9Y5H2)
Protocadherin gamma-A11 (PCDH-gamma-A11)
Gene: PCDHGA11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cadherin~Cadherin, Cadherin~Cadherin_2
Common GO terms	GO:0005509 - calcium ion binding GO:0007155 - cell adhesion GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 829 Hs			1 935
+	Hs
		1348658 CELR3_HUMAN (2-535): 8.26e-125: 416: 20.80		PCDGH_HUMAN (27-920): 0: 1002: 53.13
+	Hs
		1348654 CELR3_HUMAN (2-535): 8.26e-125: 416: 20.80		PCDGG_HUMAN (27-920): 0: 990: 52.80
+	Hs
		1378029 PCDG8_HUMAN (2-441): 7.64e-92: 311: 20.22		PCDG4_HUMAN (1-920): 0: 1025: 73.15
+	Hs
		1378028 PCDG8_HUMAN (2-441): 7.64e-92: 311: 20.22		PCDG5_HUMAN (1-920): 0: 1024: 73.80
+	Hs
		1377970 PCDB5_HUMAN (3-441): 1.25e-96: 321: 21.26		PCDB3_HUMAN (1-778): 0: 969: 44.89
+	Hs
		1377973 PCDB4_HUMAN (3-441): 5.21e-95: 316: 21.00		PCDB3_HUMAN (1-778): 0: 969: 44.89
+	Hs
		259220 CAD16_HUMAN (1-829): 0: 685: 100.00		PCDGK_HUMAN (3-457): 2.6e-96: 326: 24.95
+	Hs
		1377962 PCDBC_HUMAN (3-441): 2.13e-91: 307: 20.56		PCDB7_HUMAN (1-774): 0: 603: 44.99
+	Hs
		1336517 CELR2_HUMAN (6-696): 7.44e-159: 515: 21.43		PCDGD_HUMAN (3-445): 8.34e-103: 343: 25.33
+	Hs
		1348649 CELR1_HUMAN (2-786): 7.12e-154: 501: 19.56		PCDGD_HUMAN (3-445): 8.34e-103: 343: 25.33
+	Hs
		1167045 FAT4_HUMAN (1-761): 5.47e-145: 475: 18.49		PCDGD_HUMAN (3-445): 8.34e-103: 343: 25.33
+	Hs
		1348659 CELR3_HUMAN (2-535): 8.26e-125: 416: 20.80		PCDGD_HUMAN (3-445): 8.34e-103: 343: 25.33
+	Hs
		1348657 CELR3_HUMAN (2-535): 8.26e-125: 416: 20.80		PCDBB_HUMAN (459-924): 1e-37: 154: 14.84
+	Hs
		1378022 PCDG8_HUMAN (2-441): 7.64e-92: 311: 20.22		PCDG9_HUMAN (2-375): 5.64e-62: 229: 20.89
+	Hs
		1377971 PCDB5_HUMAN (3-441): 1.25e-96: 321: 21.26		PCDBB_HUMAN (459-924): 1e-37: 154: 14.84
+	Hs
		1377967 PCDB4_HUMAN (3-441): 5.21e-95: 316: 21.00		PCDB6_HUMAN (504-924): 7.01e-38: 154: 13.41
+	Hs
		1377968 PCDBC_HUMAN (3-441): 2.13e-91: 307: 20.56		PCDB6_HUMAN (504-924): 7.01e-38: 154: 13.41
+	Hs
		1377989 PCDBB_HUMAN (3-441): 2.91e-93: 312: 20.56		PCDBD_HUMAN (454-924): 1.95e-33: 140: 13.88
+	Hs
		1377990 PCDBB_HUMAN (3-441): 2.91e-93: 312: 20.56		PCDBC_HUMAN (760-929): 2.76e-11: 69.6: 11.56