Protein: SKI2
Superkiller complex protein 2 (Ski2) (EC 3.6.4.13) (Helicase-like protein) (HLP)

Gene: SKI2, SKIC2
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q15477

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1149464

SKI8
Superkiller complex protein 8

3

20

Small-scale

0.855

High

303563

SRP72
Signal recognition particle subunit SRP72

1

2

High-throughput

0.691

High

270362

WDR1
WD repeat-containing protein 1

1

19

High-throughput

0.656

High

1032172

EXOSX
Exosome complex component 10

1

4

High-throughput

0.656

High

447055

NPM
Nucleophosmin

2

8

High-throughput

0.628

High

345868

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

17

High-throughput

0.618

High

731328

STIP1
Stress-induced-phosphoprotein 1

1

11

High-throughput

0.618

High

945578

FBXW4
F-box/WD repeat-containing protein 4

1

20

Small-scale

0.618

High

1105935

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

9

High-throughput

0.618

High

1149431

SKI3
Superkiller complex protein 3

1

14

High-throughput

0.618

High

930703

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

3

High-throughput

0.606

High

928738

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

2

0

High-throughput

0.580

High

396175

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1149434

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.553

High

302115

CDKL5
Cyclin-dependent kinase-like 5

1

7

High-throughput

0.541

High

1149458

TSSK2
Testis-specific serine/threonine-protein kinase 2

1

3

High-throughput

0.541

High

521705

H14
Histone H1.4

1

5

High-throughput

0.536

High

571606

IRF2
Interferon regulatory factor 2

1

1

High-throughput

0.536

High

596117

H12
Histone H1.2

1

5

High-throughput

0.536

High

693758

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.536

High

832045

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

2

High-throughput

0.536

High

884097

SRP09
Signal recognition particle 9 kDa protein

1

1

High-throughput

0.536

High

956217

RAB4B
Ras-related protein Rab-4B

1

1

High-throughput

0.536

High

969877

RS16
Small ribosomal subunit protein uS9

1

4

High-throughput

0.536

High

1126411

CAPR1
Caprin-1

1

4

High-throughput

0.536

High

1149423

OASL
2'-5'-oligoadenylate synthase-like protein

1

9

High-throughput

0.536

High

1149424

SRSF7
Serine/arginine-rich splicing factor 7

1

18

High-throughput

0.536

High

1149452

PSPC1
Paraspeckle component 1

1

19

High-throughput

0.536

High

1149460

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

6

High-throughput

0.536

High

1149463

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1149468

LN28A
Protein lin-28 homolog A

1

16

High-throughput

0.536

High

1149438

DHB13
17-beta-hydroxysteroid dehydrogenase 13

1

0

High-throughput

0.513

High

574285

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

7

High-throughput

0.508

High

1149469

EXOS4
Exosome complex component RRP41

1

18

High-throughput

0.508

High

1149481

CD11A
Cyclin-dependent kinase 11A

1

7

High-throughput

0.508

High

1149435

RHOU
Rho-related GTP-binding protein RhoU

1

1

High-throughput

0.501

High

182542

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

1149442

XRN1
5'-3' exoribonuclease 1

1

6

High-throughput

0.481

High

132061

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

11

High-throughput

0.479

High

174515

TRI66
Tripartite motif-containing protein 66

1

20

High-throughput

0.479

High

241768

PRKN
E3 ubiquitin-protein ligase parkin

1

18

High-throughput

0.479

High

248300

HBP1
HMG box-containing protein 1

1

11

High-throughput

0.479

High

342194

BRD1
Bromodomain-containing protein 1

1

8

High-throughput

0.479

High

363327

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.479

High

372107

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.479

High

411987

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.479

High

588779

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

695543

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

897831

CDK9
Cyclin-dependent kinase 9

1

9

Small-scale

0.479

High

942630

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

High-throughput

0.479

High

963295

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.479

High

970560

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

1045318

TF65
Transcription factor p65

1

7

High-throughput

0.479

High

1140321

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

1149426

DUS7
Dual specificity protein phosphatase 7

1

5

High-throughput

0.479

High

1149428

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

1149429

ZN746
Zinc finger protein 746

1

5

High-throughput

0.479

High

1149437

PHF5A
PHD finger-like domain-containing protein 5A

1

1

High-throughput

0.479

High

1149439

SLN11
Schlafen family member 11

1

3

High-throughput

0.479

High

1149445

CGAS
Cyclic GMP-AMP synthase

1

3

High-throughput

0.479

High

1149446

PAPD5
Terminal nucleotidyltransferase 4B

1

8

High-throughput

0.479

High

1149447

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1149451

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

8

High-throughput

0.479

High

1149454

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1149457

CI072
Guanine nucleotide exchange factor C9orf72

1

6

High-throughput

0.479

High

1149459

PFD5
Prefoldin subunit 5

1

2

High-throughput

0.479

High

1149461

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.479

High

1149465

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.479

High

1149470

PFD4
Prefoldin subunit 4

1

2

High-throughput

0.479

High

1149471

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

1149474

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

3

High-throughput

0.479

High

1149475

TLS1
Splicing factor C9orf78

1

2

High-throughput

0.479

High

1149476

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1149477

TES
Testin

1

2

High-throughput

0.479

High

1149478

PFD2
Prefoldin subunit 2

1

2

High-throughput

0.479

High

1149479

TRI33
E3 ubiquitin-protein ligase TRIM33

1

19

High-throughput

0.479

High

1149482

RBM8A
RNA-binding protein 8A

1

20

High-throughput

0.479

High

1149484

DUS10
Dual specificity protein phosphatase 10

1

5

High-throughput

0.479

High

1149425

FSCN1
Fascin

1

0

High-throughput

0.458

High

1149427

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1149430

CDC73
Parafibromin

1

0

High-throughput

0.458

High

896383

ERF
ETS domain-containing transcription factor ERF

1

5

High-throughput

0.445

High

1056745

FMR1
Fragile X messenger ribonucleoprotein 1

1

8

High-throughput

0.445

High

1149448

DNJB8
DnaJ homolog subfamily B member 8

1

7

High-throughput

0.445

High

1149467

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.445

High

1083617

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.439

High

182126

PFD6
Prefoldin subunit 6

1

1

High-throughput

0.437

High

768273

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

879127

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

9

High-throughput

0.437

High

1149432

TTC33
Tetratricopeptide repeat protein 33

1

7

High-throughput

0.437

High

1149433

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1149444

PAF1
RNA polymerase II-associated factor 1 homolog

1

1

High-throughput

0.437

High

1149462

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

5

High-throughput

0.437

High

1149466

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.437

High

1149473

S39A9
Zinc transporter ZIP9

1

0

High-throughput

0.426

High

295584

CIB2
Calcium and integrin-binding family member 2

1

2

High-throughput

0.407

High

628411

KLK2
Kallikrein-2

1

3

High-throughput

0.407

High

1149436

SV2B
Synaptic vesicle glycoprotein 2B

1

1

High-throughput

0.407

High

1149441

CA174
UPF0688 protein C1orf174

1

1

High-throughput

0.407

High

774374

BASI
Basigin

1

0

High-throughput

0.279

Low

1149443

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1149449

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1149450

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1149483

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

1149440

GLT13
Polypeptide N-acetylgalactosaminyltransferase 13

1

0

High-throughput

0.251

Low

261810

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.249

Low

638424

FPR1
fMet-Leu-Phe receptor

1

0

High-throughput

0.232

Low

1149453

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.232

Low

1149455

S35B4
Nucleotide sugar transporter SLC35B4

1

0

High-throughput

0.232

Low

1149456

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low

1149472

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.232

Low

1149480

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025