HitPredict

Interactor 1: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Interactor 2: NIN (Q8N4C6)
Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)
Gene: NIN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 173 Hs			1 2090
+	Hs
		1233486 CC14A_HUMAN (5-169): 4.17e-36: 133: 23.78		NIN_HUMAN (1-2090): 0: 617: 100.00
+	Hs
		725123 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		MYH10_HUMAN (12-1201): 4.09e-38: 159: 12.98
+	Hs
		260524 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		MYH9_HUMAN (37-778): 5.44e-23: 110: 11.55
+	Hs
		166730 TPTE2_HUMAN (6-168): 1.11e-42: 150: 15.85		CE290_HUMAN (1326-2090): 1.25e-17: 92.4: 9.75
+	Mm
		100191 PTEN_MOUSE (5-163): 2.46e-41: 144: 18.86		TPR_MOUSE (102-839): 2.98e-17: 91.2: 10.78
+	Hs
		890672 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		PLEC_HUMAN (320-1163): 1.13e-15: 86.3: 13.21
+	Hs
		551649 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		DESP_HUMAN (1122-2071): 1.98e-15: 85.1: 11.54
+	Hs
		161658 GAK_HUMAN (9-151): 1.05e-38: 141: 17.42		GOGB1_HUMAN (1228-2090): 3.18e-16: 87.7: 10.60
+	Hs
		166798 CC14A_HUMAN (5-169): 4.17e-36: 133: 23.78		CE290_HUMAN (1326-2090): 1.25e-17: 92.4: 9.75
+	Hs
		890777 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		MY18A_HUMAN (1488-2028): 1.65e-10: 69: 18.93
+	Mm
		139397 PTEN_MOUSE (5-163): 2.46e-41: 144: 18.86		MRCKA_MOUSE (1456-1810): 2e-09: 65.2: 24.19
+	Hs
		253766 AUXI_HUMAN (9-151): 2.72e-33: 126: 15.48		MYH13_HUMAN (1382-2076): 5.15e-14: 80.5: 14.35
+	Hs
		1086089 CDKN3_HUMAN (27-171): 2.36e-28: 106: 22.29		MRCKB_HUMAN (368-855): 2.53e-13: 78.3: 18.87
+	Hs
		254484 CDKN3_HUMAN (27-171): 2.36e-28: 106: 22.29		ROCK2_HUMAN (367-978): 1.13e-12: 75.9: 17.50