HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: HELLS (Q9NRZ9)
Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)
Gene: HELLS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31417184
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus GO:0005721 - pericentric heterochromatin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 838
+	Hs
		261016 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		CHD8_HUMAN (2-836): 0: 635: 26.71
+	Hs
		260802 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		SMCA4_HUMAN (9-838): 0: 633: 24.89
+	Hs
		260883 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		229254 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		SMCA5_HUMAN (75-833): 0: 607: 30.76
+	Hs
		260763 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		SMCA1_HUMAN (104-833): 0: 596: 31.06
+	Hs
		1059910 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		1018640 H2A1H_HUMAN (1-125): 1.07e-64: 203: 62.50		CHD3_HUMAN (50-828): 0: 649: 24.79
+	Hs
		555654 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		CHD8_HUMAN (2-836): 0: 635: 26.71
+	Hs
		555359 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SMCA4_HUMAN (9-838): 0: 633: 24.89
+	Hs
		555466 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		1059717 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		1059795 H2A1H_HUMAN (1-125): 1.07e-64: 203: 62.50		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		229296 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SMCA5_HUMAN (75-833): 0: 607: 30.76
+	Hs
		229433 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		SMCA5_HUMAN (75-833): 0: 607: 30.76
+	Hs
		229279 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		SMCA5_HUMAN (75-833): 0: 607: 30.76
+	Hs
		555306 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SMCA1_HUMAN (104-833): 0: 596: 31.06
+	Hs
		151474 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		CHD2_HUMAN (5-830): 0: 596: 27.25
+	Hs
		555358 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SMCA2_HUMAN (27-838): 0: 584: 26.37
+	Hs
		555532 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		CHD1L_HUMAN (218-755): 1.8e-105: 347: 40.30
+	Hs
		1185203 H2A3_HUMAN (1-126): 8.92e-65: 203: 62.79		CHD1L_HUMAN (218-755): 1.8e-105: 347: 40.30