HitPredict

Interactor 1: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Interactor 2: ETV6 (P41212)
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)
Gene: ETV6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	11001911, 11439334
Identification Methods	pull down, affinity chromatography technology, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2440 Hs			1 452
+	Hs
		261393 NCOR1_HUMAN (1-2440): 0: 780: 100.00		ETS2_HUMAN (32-443): 5.74e-121: 362: 24.30
+	Hs
		261392 NCOR1_HUMAN (1-2440): 0: 780: 100.00		ETS1_HUMAN (5-443): 3.24e-108: 328: 21.83
+	Hs
		261385 NCOR1_HUMAN (1-2440): 0: 780: 100.00		ERG_HUMAN (254-419): 1.76e-46: 169: 29.52
+	Hs
		261575 NCOR1_HUMAN (1-2440): 0: 780: 100.00		FEV_HUMAN (294-419): 9.55e-43: 152: 28.57
+	Hs
		794577 NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71		ETV4_HUMAN (123-450): 2.88e-55: 192: 18.13
+	Hs
		507534 NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71		ERG_HUMAN (254-419): 1.76e-46: 169: 29.52
+	Hs
		1304732 NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71		FEV_HUMAN (294-419): 9.55e-43: 152: 28.57
+	Hs
		542029 SRCAP_HUMAN (1602-2436): 2.94e-20: 101: 10.64		ETS1_HUMAN (5-443): 3.24e-108: 328: 21.83
+	Hs
		507468 KMT2C_HUMAN (1352-2176): 4.42e-47: 190: 15.30		ERG_HUMAN (254-419): 1.76e-46: 169: 29.52
+	Hs
		1243834 KMT2C_HUMAN (1352-2176): 4.42e-47: 190: 15.30		FEV_HUMAN (294-419): 9.55e-43: 152: 28.57
+	Hs
		1170079 SRCAP_HUMAN (1602-2436): 2.94e-20: 101: 10.64		ELF4_HUMAN (224-436): 1.03e-51: 186: 23.32
+	Hs
		692153 SRCAP_HUMAN (1602-2436): 2.94e-20: 101: 10.64		ELF1_HUMAN (283-431): 2.79e-48: 176: 26.67
+	Hs
		1077562 SRCAP_HUMAN (1602-2436): 2.94e-20: 101: 10.64		ELF2_HUMAN (221-436): 4.72e-48: 175: 24.89
+	Hs
		1300911 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		ELF4_HUMAN (224-436): 1.03e-51: 186: 23.32
+	Hs
		1243851 KMT2C_HUMAN (1352-2176): 4.42e-47: 190: 15.30		ELF5_HUMAN (341-421): 2.02e-14: 75.1: 45.12
+	Hs
		507490 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		ERG_HUMAN (254-419): 1.76e-46: 169: 29.52
+	Hs
		1300909 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		FEV_HUMAN (294-419): 9.55e-43: 152: 28.57