HitPredict

Interactor 1: O62531 (O62531)
Adaptor protein complex 1, mu subunit (Clathrin-associated adaptor complex AP-1 medium chain) (Clathrin-associated protein) (LD31377p)
Gene: AP-1mu

Interactor 2: Q7KVR8 (Q7KVR8)
AP-1 complex subunit gamma
Gene: AP-1gamma

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22389401
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adap_comp_sub~Adaptin_N, Adaptin_N~Clat_adaptor_s
Common GO terms	GO:0006886 - intracellular protein transport GO:0030121 - AP-1 adaptor complex GO:0030136 - clathrin-coated vesicle GO:0033363 - secretory granule organization GO:0035615 - clathrin adaptor activity and 1 others more... GO:0048749 - compound eye development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 426 Dm			1 982
+	At
		199076 AP1M2_ARATH (2-424): 0: 536: 59.86		AP1G1_ARATH (39-973): 0: 690: 38.84
+	At
		1283985 AP1M1_ARATH (2-424): 0: 521: 57.28		AP1G1_ARATH (39-973): 0: 690: 38.84
+	Hs
		989100 AP1M1_HUMAN (1-425): 0: 558: 82.63		AP2B1_HUMAN (71-955): 1.9e-176: 539: 13.69
+	Hs
		1083305 AP1M1_HUMAN (1-425): 0: 558: 82.63		AP1B1_HUMAN (71-955): 1.05e-175: 538: 14.33
+	Hs
		989182 AP1M2_HUMAN (1-426): 0: 534: 75.18		AP2B1_HUMAN (71-955): 1.9e-176: 539: 13.69
+	Hs
		1083343 AP1M2_HUMAN (1-426): 0: 534: 75.18		AP1B1_HUMAN (71-955): 1.05e-175: 538: 14.33
+	Hs
		344765 AP2M1_HUMAN (5-424): 1.15e-167: 479: 40.73		AP2A1_HUMAN (37-954): 0: 588: 20.32
+	Rn
		614862 AP2M1_RAT (5-424): 1.15e-167: 479: 40.73		AP2A2_RAT (37-954): 0: 582: 22.02
+	Hs
		323765 AP2M1_HUMAN (5-424): 1.15e-167: 479: 40.73		AP2A2_HUMAN (37-954): 0: 569: 21.70
+	Ce
		773416 AP1M_CAEEL (1-424): 0: 531: 75.71		Q9N4F3_CAEEL (71-937): 4.85e-160: 497: 16.67
+	At
		199835 AP2M_ARATH (1-424): 5.1e-175: 498: 42.83		APBLB_ARATH (71-857): 1.43e-164: 507: 16.33
+	At
		199772 AP2M_ARATH (1-424): 5.1e-175: 498: 42.83		AP2A1_ARATH (42-878): 7.38e-163: 506: 22.59
+	At
		199771 AP2M_ARATH (1-424): 5.1e-175: 498: 42.83		AP2A2_ARATH (42-878): 5.26e-162: 504: 21.93
+	At
		199699 AP2M_ARATH (1-424): 5.1e-175: 498: 42.83		APBLC_ARATH (71-857): 3.11e-161: 498: 16.48
+	Hs
		225852 AP1M1_HUMAN (1-425): 0: 558: 82.63		AP1G1_HUMAN (272-974): 2.56e-51: 196: 13.41
+	Mm
		653750 AP1M1_MOUSE (1-425): 0: 556: 81.93		AP1G1_MOUSE (338-974): 7.92e-52: 198: 13.99
+	Hs
		225869 AP1M2_HUMAN (1-426): 0: 534: 75.18		AP1G1_HUMAN (272-974): 2.56e-51: 196: 13.41
+	Hs
		225845 AP2M1_HUMAN (5-424): 1.15e-167: 479: 40.73		AP1G1_HUMAN (272-974): 2.56e-51: 196: 13.41
+	Hs
		295773 AP1M2_HUMAN (1-426): 0: 534: 75.18		AP1G2_HUMAN (267-972): 1.1e-33: 141: 14.71
+	Hs
		295757 AP2M1_HUMAN (5-424): 1.15e-167: 479: 40.73		AP1G2_HUMAN (267-972): 1.1e-33: 141: 14.71