Interactor 1: ACHA4 (O70174)
Neuronal acetylcholine receptor subunit alpha-4
Gene: Chrna4
Interactor 2: ACHA5 (Q2MKA5)
Neuronal acetylcholine receptor subunit alpha-5
Gene: Chrna5
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17434683 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb |
| Common GO terms | GO:0005892 - acetylcholine-gated channel complex GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity GO:0035094 - response to nicotine GO:0035095 - behavioral response to nicotine GO:0045211 - postsynaptic membrane and 2 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025