HitPredict

Interactor 1: LNX1 (O70263)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb protein X 1) (Ligand of Numb-binding protein 1) (Numb-binding protein 1) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27889896
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098686 - hippocampal mossy fiber to CA3 synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Mm			1 245
+	Mm
		266766 LNX1_MOUSE (1-728): 1.97e-147: 449: 100.00		1433T_MOUSE (1-245): 9.02e-140: 393: 79.59
+	Hs
		990526 LNX1_HUMAN (1-728): 1.53e-134: 416: 87.57		1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59
+	Mm
		266813 LNX1_MOUSE (1-728): 1.97e-147: 449: 100.00		1433B_MOUSE (1-242): 1.98e-128: 364: 86.78
+	Mm
		990032 LNX2_MOUSE (4-728): 1.48e-113: 360: 45.42		1433Z_MOUSE (1-245): 3.49e-145: 407: 100.00
+	Mm
		266761 LNX1_MOUSE (1-728): 1.97e-147: 449: 100.00		1433G_MOUSE (1-240): 8.43e-109: 315: 74.59
+	Mm
		967120 LNX2_MOUSE (4-728): 1.48e-113: 360: 45.42		1433G_MOUSE (1-240): 8.43e-109: 315: 74.59
+	Hs
		730764 LNX2_HUMAN (9-728): 2.7e-114: 362: 45.47		1433S_HUMAN (1-237): 2.53e-103: 301: 71.55
+	Mm
		989977 DLG4_MOUSE (454-728): 1.26e-34: 142: 20.07		1433Z_MOUSE (1-245): 3.49e-145: 407: 100.00
+	Mm
		972235 DLG4_MOUSE (454-728): 1.26e-34: 142: 20.07		1433E_MOUSE (2-241): 9.95e-144: 403: 68.18
+	Hs
		990213 SCRIB_HUMAN (212-596): 5.03e-32: 136: 20.78		1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59
+	Hs
		690994 SCRIB_HUMAN (212-596): 5.03e-32: 136: 20.78		1433T_HUMAN (1-245): 2.61e-140: 395: 80.00
+	Hs
		691275 PARD3_HUMAN (233-555): 1.47e-31: 134: 20.50		1433T_HUMAN (1-245): 2.61e-140: 395: 80.00
+	Hs
		729826 SCRIB_HUMAN (212-596): 5.03e-32: 136: 20.78		1433B_HUMAN (1-242): 9.05e-140: 393: 88.02
+	Hs
		730087 PARD3_HUMAN (233-555): 1.47e-31: 134: 20.50		1433B_HUMAN (1-242): 9.05e-140: 393: 88.02
+	Mm
		1223711 DLG4_MOUSE (454-728): 1.26e-34: 142: 20.07		1433B_MOUSE (1-242): 1.98e-128: 364: 86.78
+	Ce
		92496 D3YT29_CAEEL (80-726): 9.76e-46: 177: 13.18		14331_CAEEL (5-238): 2.1e-111: 322: 79.06
+	Mm
		967108 DLG4_MOUSE (454-728): 1.26e-34: 142: 20.07		1433G_MOUSE (1-240): 8.43e-109: 315: 74.59
+	Hs
		966304 SCRIB_HUMAN (212-596): 5.03e-32: 136: 20.78		1433G_HUMAN (1-240): 8.43e-109: 315: 74.59
+	Hs
		1049282 SCRIB_HUMAN (212-596): 5.03e-32: 136: 20.78		1433F_HUMAN (2-240): 5.23e-108: 313: 74.49
+	Hs
		730579 SCRIB_HUMAN (212-596): 5.03e-32: 136: 20.78		1433S_HUMAN (1-237): 2.53e-103: 301: 71.55