HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	31710640
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 630
+	Hs
		990217 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		TRI25_HUMAN (1-630): 3.45e-145: 436: 100.00
+	Hs
		730581 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		TRI25_HUMAN (1-630): 3.45e-145: 436: 100.00
+	Mm
		267036 1433S_MOUSE (1-232): 2.01e-106: 309: 72.65		TRI25_MOUSE (1-628): 3.28e-135: 411: 72.71
+	Hs
		971969 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		TRIM9_HUMAN (4-591): 4.81e-80: 269: 14.73
+	Hs
		691404 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		TRIM4_HUMAN (169-628): 3.09e-79: 261: 14.31
+	Hs
		730869 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		TRIM9_HUMAN (4-591): 4.81e-80: 269: 14.73
+	Hs
		623235 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		RO52_HUMAN (2-263): 6.24e-30: 125: 18.32
+	Hs
		623116 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		RO52_HUMAN (2-263): 6.24e-30: 125: 18.32
+	Hs
		623259 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		RO52_HUMAN (2-263): 6.24e-30: 125: 18.32
+	Hs
		990700 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		TRIM7_HUMAN (10-413): 7.16e-25: 110: 15.00
+	Hs
		971641 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		TRI68_HUMAN (72-408): 8.54e-09: 60.5: 11.62
+	Hs
		194777 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MEFV_HUMAN (74-409): 3.47e-10: 65.1: 10.32
+	Hs
		623136 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		RO52_HUMAN (2-263): 6.24e-30: 125: 18.32
+	Hs
		623228 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		RO52_HUMAN (2-263): 6.24e-30: 125: 18.32
+	Hs
		730862 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		TRI62_HUMAN (5-318): 3.49e-20: 95.9: 19.30
+	Hs
		730670 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		TRI68_HUMAN (72-408): 8.54e-09: 60.5: 11.62