HitPredict

Interactor 1: PROP1 (O75360)
Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor)
Gene: PROP1

Interactor 2: Q6NSM0 (Q6NSM0)
NR1D2 protein (Nuclear receptor subfamily 1 group D member 2)
Gene: NR1D2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 408
+	Hs
		277096 PROP1_HUMAN (1-226): 4.2e-38: 133: 100.00		NR1D2_HUMAN (1-382): 6.68e-144: 423: 100.00
+	Mm
		1222879 Q8VD35_MOUSE (40-191): 9.48e-36: 129: 28.82		ERR2_MOUSE (5-280): 1.24e-61: 206: 25.27
+	Hs
		559724 PAX7_HUMAN (52-223): 3.27e-32: 123: 28.02		NR2C1_HUMAN (1-401): 2.74e-56: 196: 18.68
+	Hs
		559726 PAX6_HUMAN (23-226): 6.54e-31: 119: 25.47		NR2C1_HUMAN (1-401): 2.74e-56: 196: 18.68
+	Hs
		662206 PAX7_HUMAN (52-223): 3.27e-32: 123: 28.02		NR2C2_HUMAN (30-287): 3.11e-53: 188: 22.10
+	Hs
		685149 PAX6_HUMAN (23-226): 6.54e-31: 119: 25.47		ERR3_HUMAN (13-277): 1.26e-54: 189: 24.15
+	Hs
		685124 PAX6_HUMAN (23-226): 6.54e-31: 119: 25.47		NR2C2_HUMAN (30-287): 3.11e-53: 188: 22.10
+	Hs
		253021 LMX1B_HUMAN (16-196): 2.57e-29: 114: 24.60		ESR2_HUMAN (4-277): 2.5e-53: 187: 22.83
+	Dm
		197681 PITX_DROME (69-129): 3.8e-13: 69.7: 57.38		E75BB_DROME (95-202): 8.74e-50: 182: 67.59
+	Mm
		1341491 Q8VD35_MOUSE (40-191): 9.48e-36: 129: 28.82		RORB_MOUSE (100-192): 4.65e-30: 122: 59.14
+	Dm
		53823 Q9XZC2_DROME (36-226): 1.74e-29: 116: 23.38		A1Z858_DROME (100-192): 3.47e-28: 118: 54.84
+	Hs
		520588 ALX1_HUMAN (48-222): 4.75e-34: 125: 28.00		RARA_HUMAN (103-178): 6.38e-24: 105: 60.53
+	Ce
		1170887 Q22459_CAEEL (61-166): 5.02e-31: 115: 33.02		NHR91_CAEEL (35-180): 1.9e-23: 103: 41.10