HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: PHF12 (Q96QT6)
PHD finger protein 12 (PHD factor 1) (Pf1)
Gene: PHF12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26841866
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PHD
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 1004
+	Hs
		180634 H2AY_HUMAN (1-369): 6.52e-165: 467: 100.00		TIF1A_HUMAN (10-272): 2.07e-32: 138: 18.08
+	Hs
		277663 H2AY_HUMAN (1-369): 6.52e-165: 467: 100.00		BPTF_HUMAN (43-264): 2.27e-31: 135: 19.28
+	Hs
		277844 H2AY_HUMAN (1-369): 6.52e-165: 467: 100.00		BAZ2A_HUMAN (2-240): 1.88e-29: 129: 16.33
+	Hs
		277789 H2AY_HUMAN (1-369): 6.52e-165: 467: 100.00		RSF1_HUMAN (53-191): 9.37e-24: 110: 21.66
+	Hs
		277687 H2AY_HUMAN (1-369): 6.52e-165: 467: 100.00		CHD4_HUMAN (52-166): 3.05e-20: 99.6: 19.23
+	Hs
		1453893 H2AW_HUMAN (1-368): 1.42e-145: 418: 66.04		BAZ1B_HUMAN (1-239): 3.96e-32: 138: 15.52
+	Hs
		180948 H2AW_HUMAN (1-368): 1.42e-145: 418: 66.04		TIF1A_HUMAN (10-272): 2.07e-32: 138: 18.08
+	Hs
		1133015 H2AW_HUMAN (1-368): 1.42e-145: 418: 66.04		CHD4_HUMAN (52-166): 3.05e-20: 99.6: 19.23
+	Hs
		591878 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		BAZ1B_HUMAN (1-239): 3.96e-32: 138: 15.52
+	Hs
		591619 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		BPTF_HUMAN (43-264): 2.27e-31: 135: 19.28
+	Hs
		591772 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		PF21A_HUMAN (1-241): 3.05e-30: 130: 16.21
+	Hs
		591877 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		BAZ2A_HUMAN (2-240): 1.88e-29: 129: 16.33
+	Hs
		591801 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		RSF1_HUMAN (53-191): 9.37e-24: 110: 21.66
+	Hs
		591651 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		CHD4_HUMAN (52-166): 3.05e-20: 99.6: 19.23
+	Hs
		1132809 H2A2B_HUMAN (1-125): 5.81e-65: 204: 64.06		CHD4_HUMAN (52-166): 3.05e-20: 99.6: 19.23
+	Hs
		1132896 H2A1H_HUMAN (1-125): 1.08e-64: 203: 62.50		CHD4_HUMAN (52-166): 3.05e-20: 99.6: 19.23
+	Hs
		1088507 H2A1H_HUMAN (1-125): 1.08e-64: 203: 62.50		CHD3_HUMAN (11-166): 1.59e-19: 97.3: 16.96
+	Hs
		418961 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		CHD3_HUMAN (11-166): 1.59e-19: 97.3: 16.96
+	Hs
		231097 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		AIRE_HUMAN (54-114): 4.25e-16: 84.8: 44.26
+	Hs
		231160 H2A1C_HUMAN (1-126): 6e-65: 204: 62.79		AIRE_HUMAN (54-114): 4.25e-16: 84.8: 44.26