HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RAB1A (P62820)
Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein)
Gene: RAB1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0016192 - vesicle-mediated transport and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 205
+	Hs
		895026 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Hs
		895217 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		895264 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		918846 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Hs
		895216 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1C_HUMAN (4-205): 2.97e-83: 247: 87.62
+	Hs
		1273009 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		895020 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Mm
		880395 RAB4A_MOUSE (1-218): 5.01e-88: 260: 97.71		RAB1B_MOUSE (4-205): 1e-85: 253: 91.09
+	Dm
		185685 Q7KY04_DROME (6-216): 7.32e-92: 269: 77.25		O18335_DROME (1-205): 2.98e-81: 242: 45.07
+	Zm
		73944 B4FAE1_MAIZE (6-217): 7.18e-86: 254: 39.15		B4FAE1_MAIZE (4-204): 3.9e-87: 257: 78.71
+	Hs
		591800 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		894787 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		918944 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Mm
		919000 RAB1A_MOUSE (3-218): 3.01e-85: 252: 38.43		RAB1B_MOUSE (4-205): 1e-85: 253: 91.09
+	Hs
		591795 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Hs
		913992 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		918879 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		894715 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		896605 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Mm
		877189 RAB8B_MOUSE (6-205): 2.66e-90: 265: 42.00		RAB8A_MOUSE (4-199): 4.88e-74: 224: 54.08