HitPredict

Interactor 1: PIAS2 (O75928)
E3 SUMO-protein ligase PIAS2 (EC 2.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (E3 SUMO-protein transferase PIAS2) (Msx-interacting zinc finger protein) (Miz1) (PIAS-NY protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2)
Gene: PIAS2

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	18157088
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 548
+	Hs
		278315 PIAS2_HUMAN (1-621): 0: 811: 100.00		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		1317554 PIAS3_HUMAN (1-621): 0: 666: 55.25		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		278217 PIAS2_HUMAN (1-621): 0: 811: 100.00		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		278161 PIAS1_HUMAN (1-621): 0: 653: 54.10		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		1282085 PIAS3_HUMAN (1-621): 0: 666: 55.25		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		278144 PIAS1_HUMAN (1-621): 0: 653: 54.10		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		1318360 PIAS3_HUMAN (1-621): 0: 666: 55.25		TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25
+	Hs
		278295 PIAS2_HUMAN (1-621): 0: 811: 100.00		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		537154 PIAS3_HUMAN (1-621): 0: 666: 55.25		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		278162 PIAS1_HUMAN (1-621): 0: 653: 54.10		TRIM5_HUMAN (13-396): 3.08e-68: 230: 14.32
+	Hs
		277914 PIAS1_HUMAN (1-621): 0: 653: 54.10		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		536921 PIAS4_HUMAN (2-499): 1.7e-172: 502: 43.32		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		1030009 ZMIZ1_HUMAN (65-460): 1.71e-75: 262: 23.04		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		1170889 ZMIZ2_HUMAN (75-611): 9.53e-81: 275: 21.80		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		1172236 ZMIZ1_HUMAN (65-460): 1.71e-75: 262: 23.04		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39