Interactor 1: RNF8 (O76064)
E3 ubiquitin-protein ligase RNF8 (hRNF8) (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8)
Gene: RNF8

Interactor 2: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 0.60 0.619

The method score is based on:

Property Details
Experiments 23708797, 29523790
Identification Methods pull down, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006974 - DNA damage response
GO:0008270 - zinc ion binding
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 485
Hs

1 1417
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024