HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: ELP2 (Q6IA86)
Elongator complex protein 2 (ELP2) (SHINC-2) (STAT3-interacting protein 1) (StIP1)
Gene: ELP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23891004
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 826
+	Hs
		282843 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		LIS1_HUMAN (384-752): 5.32e-38: 148: 11.54
+	Hs
		1240442 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		POC1A_HUMAN (514-826): 8.97e-55: 196: 13.06
+	Hs
		282789 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		CIAO1_HUMAN (565-792): 8.89e-09: 59.9: 17.80
+	Hs
		245633 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		TBL1X_HUMAN (647-823): 1.51e-14: 79.6: 11.72
+	Hs
		1346954 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		NLE1_HUMAN (467-826): 1.07e-51: 190: 12.56
+	Hs
		903551 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		NLE1_HUMAN (467-826): 1.07e-51: 190: 12.56
+	Hs
		254111 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		WDR1_HUMAN (7-254): 2.09e-15: 82.2: 14.29
+	Hs
		792949 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		LIS1_HUMAN (384-752): 5.32e-38: 148: 11.54
+	Hs
		1288390 SNR40_HUMAN (234-339): 2.57e-15: 77.8: 19.81		WDR3_HUMAN (5-281): 5.06e-37: 152: 14.19
+	Mm
		925836 LIS1_MOUSE (224-339): 4.97e-16: 80.1: 15.52		LIS1_MOUSE (384-752): 3.6e-38: 149: 11.54
+	Hs
		792935 LIS1_HUMAN (224-339): 5.41e-16: 80.1: 15.52		LIS1_HUMAN (384-752): 5.32e-38: 148: 11.54
+	Hs
		903174 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		TBL3_HUMAN (2-142): 4.37e-26: 116: 23.40
+	Sp
		999838 TUP11_SCHPO (175-339): 1.79e-29: 120: 15.76		TUP11_SCHPO (696-826): 6.85e-13: 74.2: 8.40
+	Hs
		1016312 SNR40_HUMAN (234-339): 2.57e-15: 77.8: 19.81		TBL3_HUMAN (2-142): 4.37e-26: 116: 23.40
+	Sp
		999842 TUP11_SCHPO (175-339): 1.79e-29: 120: 15.76		TUP12_SCHPO (696-826): 3.61e-10: 65.4: 7.63
+	Hs
		245630 TBL1Y_HUMAN (58-218): 5.74e-14: 74.3: 28.24		TBL1X_HUMAN (647-823): 1.51e-14: 79.6: 11.72
+	Hs
		282871 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		CIAO1_HUMAN (565-792): 8.89e-09: 59.9: 17.80
+	Hs
		1309163 TBL1Y_HUMAN (58-218): 5.74e-14: 74.3: 28.24		TBL1R_HUMAN (382-696): 4.63e-11: 68: 17.80