HitPredict

Interactor 1: WBP4 (O75554)
WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21) (WW domain-containing-binding protein 4)
Gene: WBP4

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	16055720
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 551
+	Hs
		286483 WBP4_HUMAN (1-376): 3.95e-99: 300: 100.00		CPSF7_HUMAN (1-525): 2.62e-45: 168: 40.63
+	Hs
		280638 PR40A_HUMAN (98-260): 1.45e-31: 128: 21.47		CPSF6_HUMAN (1-520): 4.07e-90: 289: 100.00
+	Hs
		286425 WBP4_HUMAN (1-376): 3.95e-99: 300: 100.00		PABP1_HUMAN (81-480): 2.69e-24: 109: 12.35
+	Hs
		132073 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		CPSF6_HUMAN (1-520): 4.07e-90: 289: 100.00
+	Dm
		1484287 Q9VQK5_DROME (120-358): 9.63e-43: 160: 16.14		CPSF6_DROME (8-485): 4.27e-44: 167: 36.77
+	Hs
		280725 PR40A_HUMAN (98-260): 1.45e-31: 128: 21.47		CPSF7_HUMAN (1-525): 2.62e-45: 168: 40.63
+	Hs
		131836 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		SMCA2_HUMAN (179-551): 1.49e-44: 171: 15.35
+	Hs
		132164 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		CPSF7_HUMAN (1-525): 2.62e-45: 168: 40.63
+	Hs
		131837 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		SMCA4_HUMAN (126-551): 4.41e-41: 161: 16.18
+	Hs
		132273 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		DIDO1_HUMAN (122-548): 3.32e-26: 116: 17.64
+	Sc
		403427 PRP40_YEAST (126-271): 6.72e-26: 110: 21.92		PABP_YEAST (74-170): 2.96e-12: 71.1: 26.53
+	Hs
		131699 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		PABP1_HUMAN (81-480): 2.69e-24: 109: 12.35
+	Hs
		131637 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		SC24D_HUMAN (131-353): 1.99e-11: 68.8: 21.49
+	Hs
		132010 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		PABP4_HUMAN (74-172): 3.37e-10: 64.9: 17.00
+	Hs
		131851 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		SC24C_HUMAN (246-440): 4.68e-10: 64.5: 17.81
+	Mm
		1298188 WWP2_MOUSE (43-243): 4.34e-12: 69.7: 14.90		DIDO1_MOUSE (146-450): 9.99e-10: 63.7: 17.09
+	Hs
		132284 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		WDR33_HUMAN (180-396): 5.24e-09: 61.5: 24.69