Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6
Interactor 2: WNT3 (P56703)
Proto-oncogene Wnt-3 (Proto-oncogene Int-4 homolog)
Gene: WNT3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.60 | 0.501 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31036956 |
| Identification Methods | surface plasmon resonance |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005109 - frizzled binding GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0060070 - canonical Wnt signaling pathway GO:1904948 - midbrain dopaminergic neuron differentiation and 1 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025