Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6
Interactor 2: WNT3A (P56704)
Protein Wnt-3a
Gene: WNT3A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 0.60 | 0.709 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 19910923, 21944579, unassigned3799, 22726442 |
| Identification Methods | affinity chromatography technology, bio-layer interferometry, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005102 - signaling receptor binding GO:0005109 - frizzled binding GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0009986 - cell surface and 6 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025