Interactor 1: SAP30 (O88574)
Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30)
Gene: SAP30

Interactor 2: SIN3A (Q60520)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.49 1.00 0.700

The method score is based on:

Property Details
Experiments 9702189
Identification Methods coimmunoprecipitation, pull down, anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PAH~SAP30_Sin3_bdg
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
and 7 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 220
Mm

1 1274
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024