HitPredict

Interactor 1: CD123 (O75794)
Translation initiation factor eIF2 assembly protein (Cell division cycle protein 123 homolog) (Protein D123) (HT-1080) (PZ32)
Gene: CDC123

Interactor 2: K2C74 (Q7RTS7)
Keratin, type II cytoskeletal 74 (Cytokeratin-74) (CK-74) (Keratin-5c) (K5C) (Keratin-74) (K74) (Type II inner root sheath-specific keratin-K6irs4) (Type-II keratin Kb37)
Gene: KRT74

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37314216
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 336 Hs			1 529
+	Hs
		293301 CD123_HUMAN (1-336): 0: 567: 100.00		K22E_HUMAN (112-456): 3.27e-150: 446: 67.54
+	Hs
		293126 CD123_HUMAN (1-336): 0: 567: 100.00		K2C3_HUMAN (88-458): 4.9e-147: 437: 66.49
+	Hs
		294002 CD123_HUMAN (1-336): 0: 567: 100.00		K2C78_HUMAN (78-470): 1.82e-132: 396: 58.78
+	Hs
		293059 CD123_HUMAN (1-336): 0: 567: 100.00		K2C8_HUMAN (112-480): 3.64e-130: 389: 58.81
+	Hs
		293936 CD123_HUMAN (1-336): 0: 567: 100.00		K2C1B_HUMAN (45-471): 1.98e-110: 342: 57.27
+	Hs
		293138 CD123_HUMAN (1-336): 0: 567: 100.00		K2C5_HUMAN (1-456): 1.3e-82: 270: 57.85
+	Hs
		293035 CD123_HUMAN (1-336): 0: 567: 100.00		K2C6B_HUMAN (2-472): 6.1e-81: 264: 56.80
+	Hs
		293363 CD123_HUMAN (1-336): 0: 567: 100.00		K2C6C_HUMAN (2-472): 1.24e-80: 264: 56.80
+	Hs
		293020 CD123_HUMAN (1-336): 0: 567: 100.00		K2C6A_HUMAN (2-472): 7.02e-77: 254: 57.00
+	Hs
		293686 CD123_HUMAN (1-336): 0: 567: 100.00		K1H2_HUMAN (18-462): 4.45e-67: 225: 21.57