Protein: HORN
Hornerin

Gene: HORN, HRNR
Organism: Homo sapiens
Interactions: 132
UniProt ID: Q86YZ3

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

387043

P53
Cellular tumor antigen p53

1

16

Small-scale

0.618

High

1125327

FILA2
Filaggrin-2

1

20

High-throughput

0.618

High

227962

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

927263

1433Z
14-3-3 protein zeta/delta

2

2

Small-scale

0.584

High

961184

HSF1
Heat shock factor protein 1

2

5

High-throughput

0.584

High

1046094

DX39B
Spliceosome RNA helicase DDX39B

2

8

Small-scale

0.584

High

1206188

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

3

High-throughput

0.554

High

127115

FOXN3
Forkhead box protein N3

1

5

High-throughput

0.536

High

336539

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

345112

CYTA
Cystatin-A

1

2

High-throughput

0.536

High

414980

CDK1
Cyclin-dependent kinase 1

1

10

High-throughput

0.536

High

440607

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.536

High

529371

CFTR
Cystic fibrosis transmembrane conductance regulator

1

8

High-throughput

0.536

High

601298

VDAC1
Voltage-dependent anion-selective channel protein 1

1

1

High-throughput

0.536

High

851575

NEK4
Serine/threonine-protein kinase Nek4

1

14

High-throughput

0.536

High

986384

BTK
Tyrosine-protein kinase BTK

1

1

Small-scale

0.536

High

1062761

FL2D
Pre-mRNA-splicing regulator WTAP

1

1

High-throughput

0.536

High

1065956

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

2

High-throughput

0.536

High

1199064

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

4

High-throughput

0.536

High

1206175

STYX
Serine/threonine/tyrosine-interacting protein

1

1

Small-scale

0.536

High

1206177

CSN5
COP9 signalosome complex subunit 5

1

6

High-throughput

0.536

High

1206199

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

4

High-throughput

0.536

High

1206201

ANLN
Anillin

2

6

High-throughput

0.533

High

455621

PARP1
Poly [ADP-ribose] polymerase 1

1

7

High-throughput

0.515

High

679623

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.513

High

1086071

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.513

High

1206189

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.513

High

432029

HS90A
Heat shock protein HSP 90-alpha

1

4

Small-scale

0.501

High

476013

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

1206178

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.501

High

1206211

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.493

High

725826

SOAT1
Sterol O-acyltransferase 1

1

1

High-throughput

0.489

High

1041388

CUL2
Cullin-2

1

9

High-throughput

0.489

High

1206203

POTE1
Protection of telomeres protein 1

1

1

High-throughput

0.489

High

62599

DPRX
Divergent paired-related homeobox

1

11

High-throughput

0.479

High

134113

DDX3X
ATP-dependent RNA helicase DDX3X

1

8

Small-scale

0.479

High

206284

RA51C
DNA repair protein RAD51 homolog 3

1

2

High-throughput

0.479

High

210111

PRC1
Protein regulator of cytokinesis 1

1

3

High-throughput

0.479

High

260498

PITX3
Pituitary homeobox 3

1

10

Small-scale

0.479

High

282690

RNF8
E3 ubiquitin-protein ligase RNF8

1

11

High-throughput

0.479

High

301913

TRI37
E3 ubiquitin-protein ligase TRIM37

1

16

High-throughput

0.479

High

303344

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

338660

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

347240

MYC
Myc proto-oncogene protein

1

16

High-throughput

0.479

High

369946

ESR1
Estrogen receptor

1

20

High-throughput

0.479

High

374490

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

13

High-throughput

0.479

High

379579

MYCN
N-myc proto-oncogene protein

1

16

High-throughput

0.479

High

450909

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.479

High

453455

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

4

High-throughput

0.479

High

456605

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

5

Small-scale

0.479

High

487574

ANDR
Androgen receptor

1

18

High-throughput

0.479

High

542377

PLAK
Junction plakoglobin

1

7

High-throughput

0.479

High

548818

HIS3
Histatin-3

1

2

Small-scale

0.479

High

551768

DESP
Desmoplakin

1

3

High-throughput

0.479

High

572399

LEG3
Galectin-3

1

2

Small-scale

0.479

High

591006

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

596007

EFNA1
Ephrin-A1

1

2

High-throughput

0.479

High

625507

CDK2
Cyclin-dependent kinase 2

1

10

High-throughput

0.479

High

734677

TRI23
E3 ubiquitin-protein ligase TRIM23

1

4

High-throughput

0.479

High

779698

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

808747

YAP1
Transcriptional coactivator YAP1

1

5

High-throughput

0.479

High

830763

ARL4D
ADP-ribosylation factor-like protein 4D

1

7

High-throughput

0.479

High

832565

MCM2
DNA replication licensing factor MCM2

1

8

High-throughput

0.479

High

870845

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

Small-scale

0.479

High

875091

TERA
Transitional endoplasmic reticulum ATPase

1

4

Small-scale

0.479

High

908775

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

950517

ARF1
ADP-ribosylation factor 1

1

3

High-throughput

0.479

High

950649

ARF5
ADP-ribosylation factor 5

1

3

High-throughput

0.479

High

962851

MDM2
E3 ubiquitin-protein ligase Mdm2

1

9

Small-scale

0.479

High

964940

FABP5
Fatty acid-binding protein 5

1

1

High-throughput

0.479

High

966589

OTUD4
OTU domain-containing protein 4

1

1

High-throughput

0.479

High

967263

EWS
RNA-binding protein EWS

1

15

High-throughput

0.479

High

969829

KIF23
Kinesin-like protein KIF23

1

11

High-throughput

0.479

High

970810

DSG1
Desmoglein-1

1

5

High-throughput

0.479

High

980284

K1C17
Keratin, type I cytoskeletal 17

1

3

High-throughput

0.479

High

1018566

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

9

High-throughput

0.479

High

1043087

CUL4A
Cullin-4A

1

9

High-throughput

0.479

High

1043927

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

10

High-throughput

0.479

High

1059716

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

9

High-throughput

0.479

High

1116373

LARP7
La-related protein 7

1

5

High-throughput

0.479

High

1134360

KPRP
Keratinocyte proline-rich protein

1

1

High-throughput

0.479

High

1139230

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

1

High-throughput

0.479

High

1140588

RN123
E3 ubiquitin-protein ligase RNF123

1

7

High-throughput

0.479

High

1170676

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

1204732

CEP57
Centrosomal protein of 57 kDa

1

3

High-throughput

0.479

High

1206171

RHG24
Rho GTPase-activating protein 24

1

11

High-throughput

0.479

High

1206176

HDAC2
Histone deacetylase 2

1

7

High-throughput

0.479

High

1206181

ARMC5
Armadillo repeat-containing protein 5

1

4

High-throughput

0.479

High

1206183

AURKB
Aurora kinase B

1

10

High-throughput

0.479

High

1206186

SPB12
Serpin B12

1

8

High-throughput

0.479

High

1206187

CIC
Protein capicua homolog

1

17

High-throughput

0.479

High

1206190

NECD
Necdin

1

5

High-throughput

0.479

High

1206191

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.479

High

1206192

TRIM6
Tripartite motif-containing protein 6

1

3

Small-scale

0.479

High

1206194

PRD14
PR domain zinc finger protein 14

1

5

Small-scale

0.479

High

1206195

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1206196

TXNIP
Thioredoxin-interacting protein

1

12

Small-scale

0.479

High

1206197

CHM4B
Charged multivesicular body protein 4b

1

8

High-throughput

0.479

High

1206198

SENP2
Sentrin-specific protease 2

1

4

Small-scale

0.479

High

1206200

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

6

High-throughput

0.479

High

1206202

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

1206204

HDAC6
Histone deacetylase 6

1

10

High-throughput

0.479

High

1206205

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

1206206

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

7

Small-scale

0.479

High

1206209

FBW1A
F-box/WD repeat-containing protein 1A

1

6

High-throughput

0.479

High

1206210

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

13

Small-scale

0.479

High

1206212

RNF11
RING finger protein 11

1

4

Small-scale

0.479

High

1206180

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

1

High-throughput

0.470

High

242108

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

1026308

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

1184199

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1206208

FAF1
FAS-associated factor 1

1

0

High-throughput

0.458

High

1046708

KLF5
Krueppel-like factor 5

1

12

High-throughput

0.457

High

497264

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.445

High

1030594

STF1
Steroidogenic factor 1

1

11

Small-scale

0.445

High

1130287

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

1139571

RNLS
Renalase

1

1

Small-scale

0.445

High

1206172

RYBP
RING1 and YY1-binding protein

1

4

High-throughput

0.445

High

1206207

AGO2
Protein argonaute-2

1

2

High-throughput

0.445

High

488754

ARAF
Serine/threonine-protein kinase A-Raf

1

13

High-throughput

0.437

High

856329

EFNA3
Ephrin-A3

1

2

High-throughput

0.437

High

1206170

CUL9
Cullin-9

1

4

Small-scale

0.437

High

1206173

ARL10
ADP-ribosylation factor-like protein 10

1

5

High-throughput

0.437

High

1206174

CEP76
Centrosomal protein of 76 kDa

1

1

High-throughput

0.437

High

1206179

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

5

Small-scale

0.437

High

1206182

RNF31
E3 ubiquitin-protein ligase RNF31

1

16

High-throughput

0.437

High

1206185

DIRA2
GTP-binding protein Di-Ras2

1

2

Small-scale

0.437

High

1206193

DDX24
ATP-dependent RNA helicase DDX24

1

8

High-throughput

0.437

High

1206213

PPME1
Protein phosphatase methylesterase 1

1

1

Small-scale

0.437

High

1080

SIM26
Small integral membrane protein 26

1

1

High-throughput

0.407

High

1206184

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

1053597

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024