HitPredict

Interactor 1: SC5D (O75845)
Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase)
Gene: SC5D

Interactor 2: RL3R2 (Q8TDU9)
Relaxin-3 receptor 2 (RLN3 receptor 2) (G-protein coupled receptor 100) (G-protein coupled receptor GPCR142) (Insulin-like peptide INSL5 receptor) (Relaxin family peptide receptor 4)
Gene: RXFP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 299 Hs			1 374
+	Hs
		295913 SC5D_HUMAN (1-299): 1.99e-125: 361: 100.00		CCR6_HUMAN (39-336): 5.67e-85: 264: 25.82
+	Hs
		295928 SC5D_HUMAN (1-299): 1.99e-125: 361: 100.00		CML1_HUMAN (32-327): 1.9e-24: 104: 26.75
+	Hs
		295905 SC5D_HUMAN (1-299): 1.99e-125: 361: 100.00		C5AR1_HUMAN (40-309): 3.9e-23: 100: 30.69
+	Hs
		771128 MSMO1_HUMAN (37-263): 1.27e-56: 185: 23.53		APJ_HUMAN (16-365): 1.88e-71: 229: 23.90
+	Hs
		352806 CH25H_HUMAN (135-262): 3.8e-33: 124: 23.88		CCR4_HUMAN (40-328): 3.2e-69: 223: 26.80
+	Hs
		638425 MSMO1_HUMAN (37-263): 1.27e-56: 185: 23.53		FPR1_HUMAN (4-320): 1.53e-26: 110: 29.00
+	Hs
		668995 MSMO1_HUMAN (37-263): 1.27e-56: 185: 23.53		FPR2_HUMAN (35-320): 1.23e-25: 107: 28.62
+	Hs
		1154052 MSMO1_HUMAN (37-263): 1.27e-56: 185: 23.53		P2RY8_HUMAN (37-315): 2.27e-23: 101: 30.64