Interactor 1: PAK3 (O75914)
Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)
Gene: PAK3

Interactor 2: PAK2 (Q13177)
Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]
Gene: PAK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~PBD, PBD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 10 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 559
Hs

1 524
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Rn
+ Rn
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Mm
+ Hs
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025