HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras, Arm_3~Ras
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 696 Hs			1 538
+	Hs
		853554 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		853220 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Hs
		213990 SPOP_HUMAN (300-648): 8.45e-74: 244: 15.32		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	At
		186838 BPM3_ARATH (301-668): 1.61e-72: 242: 14.00		IMPA1_ARATH (4-538): 9.01e-160: 467: 52.78
+	Hs
		238654 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Hs
		214155 SPOP_HUMAN (300-648): 8.45e-74: 244: 15.32		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		168602 SPOP_HUMAN (300-648): 8.45e-74: 244: 15.32		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Hs
		853562 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		134868 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Hs
		545276 RAC2_HUMAN (12-219): 3.63e-71: 231: 36.97		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		853556 RHOA_HUMAN (16-215): 2.02e-68: 224: 36.45		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		853234 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36