HitPredict

Interactor 1: MICA2 (O94851)
[F-actin]-monooxygenase MICAL2 (EC 1.14.13.225) (MICAL C-terminal-like protein) (Mical-cL) (Molecule interacting with CasL protein 2) (MICAL-2)
Gene: MICAL2

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28007913
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1957 Hs			1 870
+	Mm
		222871 MICA3_MOUSE (1-1957): 0: 1169: 35.86		ACK1_MOUSE (9-581): 1.34e-29: 128: 13.93
+	Hs
		1054784 MICA1_HUMAN (8-896): 0: 973: 39.49		CASL_HUMAN (1-868): 1.02e-91: 309: 35.96
+	Hs
		1056876 MICA3_HUMAN (1-1957): 0: 1124: 34.98		MDC1_HUMAN (48-774): 9.36e-10: 64.9: 9.16
+	Hs
		1255767 MICA1_HUMAN (8-896): 0: 973: 39.49		CASS4_HUMAN (4-865): 6.37e-38: 154: 19.91
+	Hs
		261231 FLNB_HUMAN (480-1721): 8.73e-71: 267: 10.28		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		882242 SPTB2_HUMAN (480-801): 3.1e-57: 222: 19.58		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		521513 ACTN1_HUMAN (480-757): 2e-57: 218: 23.96		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		1068700 PLEC_HUMAN (480-1932): 1.04e-79: 296: 13.32		MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79
+	Hs
		598334 FLNA_HUMAN (480-1721): 2.03e-78: 292: 11.59		CASS4_HUMAN (4-865): 6.37e-38: 154: 19.91
+	Hs
		598120 FLNA_HUMAN (480-1721): 2.03e-78: 292: 11.59		MDC1_HUMAN (48-774): 9.36e-10: 64.9: 9.16
+	Hs
		598253 FLNA_HUMAN (480-1721): 2.03e-78: 292: 11.59		TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93
+	Mm
		222846 SPTB2_MOUSE (480-801): 3.1e-57: 222: 19.58		ACK1_MOUSE (9-581): 1.34e-29: 128: 13.93
+	Hs
		261264 FLNB_HUMAN (480-1721): 8.73e-71: 267: 10.28		MDC1_HUMAN (48-774): 9.36e-10: 64.9: 9.16
+	Hs
		993278 ACTN3_HUMAN (485-749): 1.39e-58: 222: 25.46		TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93
+	Hs
		725681 ACTN2_HUMAN (480-757): 7.66e-58: 219: 22.92		TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93
+	Hs
		521586 ACTN1_HUMAN (480-757): 2e-57: 218: 23.96		TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93
+	Hs
		211629 ACTN4_HUMAN (480-757): 7.37e-57: 217: 22.57		TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93
+	Dm
		113976 M9PB30_DROME (1201-1837): 5.23e-28: 126: 10.67		M9PB30_DROME (48-545): 8.86e-17: 88: 12.02
+	Ce
		136783 O17566_CAEEL (1191-1952): 1.05e-13: 79.3: 10.84		UNC89_CAEEL (64-345): 5.87e-13: 75.6: 13.42
+	Mm
		1351630 PCLO_MOUSE (1152-1780): 4.28e-16: 87.4: 10.64		PCLO_MOUSE (15-743): 1.43e-09: 64.5: 10.52