HitPredict

Interactor 1: K0754 (O94854)
Microtubule-actin cross-linking factor 1, isoforms 6/7 (Uncharacterized protein KIAA0754)
Gene: MACF1

Interactor 2: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3515 Hs			1 192
+	Hs
		297823 K0754_HUMAN (1-3515): 0: 1797: 100.00		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		297819 K0754_HUMAN (1-3515): 0: 1797: 100.00		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		297827 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Hs
		297820 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		297809 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79
+	Hs
		164599 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		164564 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03
+	Hs
		164589 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		164602 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Hs
		164590 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		164593 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		164556 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79
+	Hs
		925201 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		564483 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03
+	Hs
		545327 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00
+	Hs
		892322 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		950929 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Hs
		893910 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		900386 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		436258 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79