HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23891004
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 305
+	Hs
		302772 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		LIS1_HUMAN (2-262): 1.72e-86: 266: 20.64
+	Hs
		302801 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		984306 GBB2_HUMAN (77-339): 2.99e-44: 156: 16.98		NLE1_HUMAN (7-304): 8.2e-91: 279: 21.61
+	Hs
		1380064 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Hs
		1450936 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		NLE1_HUMAN (7-304): 8.2e-91: 279: 21.61
+	Hs
		845264 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		LIS1_HUMAN (2-262): 1.72e-86: 266: 20.64
+	Sp
		1068486 TUP11_SCHPO (175-339): 1.15e-29: 120: 15.76		TUP12_SCHPO (97-303): 1.5e-64: 214: 30.52
+	Hs
		1334151 POC1B_HUMAN (92-339): 5.35e-60: 201: 20.97		POC1A_HUMAN (2-133): 1.59e-33: 128: 20.46
+	Hs
		965141 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Sp
		1068482 TUP11_SCHPO (175-339): 1.15e-29: 120: 15.76		TUP11_SCHPO (131-303): 6.71e-50: 176: 27.62
+	Dm
		1463921 WDS_DROME (137-339): 6.23e-48: 166: 20.69		Q9VYQ9_DROME (181-304): 8.18e-34: 130: 25.81
+	Ce
		1372650 SEL10_CAEEL (6-275): 1.5e-49: 176: 24.72		SEL10_CAEEL (3-171): 8.57e-24: 103: 20.00
+	Dm
		1463923 WDS_DROME (137-339): 6.23e-48: 166: 20.69		FBXW7_DROME (217-304): 2.95e-19: 90.2: 24.72
+	Hs
		965071 WDR5B_HUMAN (2-132): 1.34e-25: 106: 22.06		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Dm
		1463899 WDS_DROME (137-339): 6.23e-48: 166: 20.69		WDS_DROME (2-95): 1.03e-16: 81.2: 21.88
+	Hs
		938199 SEC13_HUMAN (28-281): 8.1e-19: 87.4: 29.64		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		965276 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		964797 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Ca
		515422 TUP1_CANAL (180-338): 2.08e-28: 116: 18.87		TUP1_CANAL (4-95): 2.39e-12: 68.8: 23.96
+	Hs
		209230 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		PRP4_HUMAN (218-304): 3.01e-14: 74.6: 13.68