HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17041588
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 334
+	Hs
		302772 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		LIS1_HUMAN (2-289): 9.62e-95: 288: 29.49
+	Hs
		965141 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00
+	Hs
		965071 WDR5B_HUMAN (2-132): 1.34e-25: 106: 22.06		WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00
+	Hs
		938199 SEC13_HUMAN (28-281): 8.1e-19: 87.4: 29.64		WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00
+	Hs
		965276 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00
+	Dm
		1463921 WDS_DROME (137-339): 6.23e-48: 166: 20.69		Q9VYQ9_DROME (12-333): 2.57e-94: 290: 26.67
+	Dm
		1463899 WDS_DROME (137-339): 6.23e-48: 166: 20.69		WDS_DROME (3-290): 6.4e-92: 279: 31.21
+	Hs
		845264 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		LIS1_HUMAN (2-289): 9.62e-95: 288: 29.49
+	Hs
		222461 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		PLRG1_HUMAN (2-333): 4.67e-85: 267: 26.05
+	Hs
		1180240 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		SMU1_HUMAN (30-331): 7.69e-39: 145: 28.71
+	Hs
		1380064 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		FBXW7_HUMAN (198-333): 3.33e-28: 117: 30.15
+	Hs
		984306 GBB2_HUMAN (77-339): 2.99e-44: 156: 16.98		NLE1_HUMAN (197-332): 2.62e-33: 130: 22.54
+	Hs
		1334151 POC1B_HUMAN (92-339): 5.35e-60: 201: 20.97		POC1A_HUMAN (10-75): 3.84e-14: 74.6: 22.73
+	Ce
		1372650 SEL10_CAEEL (6-275): 1.5e-49: 176: 24.72		SEL10_CAEEL (40-214): 3.52e-21: 96.3: 29.05
+	Dm
		1463923 WDS_DROME (137-339): 6.23e-48: 166: 20.69		FBXW7_DROME (40-169): 6.74e-18: 86.7: 39.10
+	Sp
		1068482 TUP11_SCHPO (175-339): 1.15e-29: 120: 15.76		TUP11_SCHPO (3-117): 8.27e-32: 127: 25.19
+	Sp
		1068486 TUP11_SCHPO (175-339): 1.15e-29: 120: 15.76		TUP12_SCHPO (2-118): 8.57e-31: 123: 20.30
+	Hs
		1450936 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		NLE1_HUMAN (197-332): 2.62e-33: 130: 22.54
+	Hs
		209230 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		PRP4_HUMAN (212-333): 3.64e-24: 104: 25.98
+	Ca
		515422 TUP1_CANAL (180-338): 2.08e-28: 116: 18.87		TUP1_CANAL (5-76): 8.28e-11: 64.6: 20.00