Interactor 1: S12A2 (A0A0G2KTI4)
Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) (BSC2) (Na-K-Cl cotransporter 1) (NKCC1)
Gene: slc12a2
Interactor 2: S12A2 (A0A0G2KTI4)
Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) (BSC2) (Na-K-Cl cotransporter 1) (NKCC1)
Gene: slc12a2
Species: Danio rerio
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.34 | 1.00 | 0.584 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31367042 |
| Identification Methods | 3D electron microscopy |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AA_permease~AA_permease, AA_permease~AA_permease_N, AA_permease~SLC12, AA_permease_N~SLC12, SLC12~SLC12 |
| Common GO terms | GO:0006884 - cell volume homeostasis GO:0008511 - sodium:potassium:chloride symporter activity GO:0008519 - ammonium channel activity GO:0015377 - chloride:monoatomic cation symporter activity GO:0016323 - basolateral plasma membrane and 12 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025