HitPredict

Interactor 1: A0A0J9YVR0 (A0A0J9YVR0)
Phosphatase and actin regulator 4
Gene: PHACTR4

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Actin~RPEL
Common GO terms	GO:0005737 - cytoplasm GO:0030027 - lamellipodium GO:0051726 - regulation of cell cycle
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 221 Hs			1 375
+	Hs
		257143 PHAR2_HUMAN (17-164): 1.7e-45: 161: 43.92		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		257126 PHAR2_HUMAN (17-164): 1.7e-45: 161: 43.92		POTEI_HUMAN (1-375): 0: 731: 91.20
+	Hs
		891891 PHAR4_HUMAN (10-212): 4.85e-75: 241: 98.03		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		929922 PHAR4_HUMAN (10-212): 4.85e-75: 241: 98.03		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		932253 PHAR4_HUMAN (10-212): 4.85e-75: 241: 98.03		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		891978 PHAR3_HUMAN (1-186): 1.24e-59: 197: 28.50		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		932331 PHAR3_HUMAN (1-186): 1.24e-59: 197: 28.50		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		933050 PHAR1_HUMAN (16-183): 1.47e-58: 195: 39.29		ACTS_HUMAN (2-375): 0: 592: 93.58
+	Hs
		257134 PHAR2_HUMAN (17-164): 1.7e-45: 161: 43.92		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		257139 PHAR2_HUMAN (17-164): 1.7e-45: 161: 43.92		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		257140 PHAR2_HUMAN (17-164): 1.7e-45: 161: 43.92		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		257136 PHAR2_HUMAN (17-164): 1.7e-45: 161: 43.92		ACTA_HUMAN (2-375): 0: 591: 94.12
+	Dm
		501561 Q9VZM9_DROME (24-124): 4.61e-26: 107: 42.16		ACT1_DROME (2-375): 0: 598: 98.13