Protein: S12A5
Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (hKCC2) (Neuronal K-Cl cotransporter)

Gene: S12A5, SLC12A5
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q9H2X9

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0006884 - cell volume homeostasis
GO:0006971 - hypotonic response
GO:0007268 - chemical synaptic transmission

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1432288

S12A4
Solute carrier family 12 member 4

2

13

High-throughput

0.712

High

1432286

S12A6
Solute carrier family 12 member 6

1

13

High-throughput

0.575

High

1432291

S12A7
Solute carrier family 12 member 7

1

14

High-throughput

0.575

High

906981

CCR4
C-C chemokine receptor type 4

1

14

High-throughput

0.541

High

936121

PAR2
Proteinase-activated receptor 2

1

19

High-throughput

0.541

High

906929

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

1398438

YTDC1
YTH domain-containing protein 1

1

0

High-throughput

0.493

High

122846

KIF2A
Kinesin-like protein KIF2A

1

1

High-throughput

0.445

High

291535

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.445

High

461926

HS90A
Heat shock protein HSP 90-alpha

1

10

High-throughput

0.445

High

468795

HS90B
Heat shock protein HSP 90-beta

1

10

High-throughput

0.445

High

627567

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

3

High-throughput

0.445

High

761512

HS71L
Heat shock 70 kDa protein 1-like

1

14

High-throughput

0.445

High

857174

NSF
Vesicle-fusing ATPase

1

1

High-throughput

0.445

High

1004195

CXAR
Coxsackievirus and adenovirus receptor

1

7

High-throughput

0.445

High

1038701

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

16

High-throughput

0.445

High

1106068

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

16

High-throughput

0.445

High

1143791

PON2
Serum paraoxonase/arylesterase 2

1

1

High-throughput

0.445

High

1158537

CDC37
Hsp90 co-chaperone Cdc37

1

3

High-throughput

0.445

High

1312253

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.445

High

1432287

BAG5
BAG family molecular chaperone regulator 5

1

10

High-throughput

0.445

High

1432289

ITM2B
Integral membrane protein 2B

1

5

High-throughput

0.445

High

106641

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

933053

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.426

High

1432284

VEZA
Vezatin

1

0

High-throughput

0.426

High

170958

CLGN
Calmegin

1

11

High-throughput

0.407

High

731608

STIP1
Stress-induced-phosphoprotein 1

1

13

High-throughput

0.407

High

1119459

CASP
Protein CASP

1

5

High-throughput

0.407

High

1328200

JAGN1
Protein jagunal homolog 1

1

3

High-throughput

0.407

High

1432290

SGT1
Protein SGT1 homolog

1

6

High-throughput

0.407

High

1164235

DGUOK
Deoxyguanosine kinase, mitochondrial

3

0

High-throughput

0.347

High

1432285

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.347

High


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Last updated: 11Aug2025