Interactor 1: S12A5 (Q9H2X9)
Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (hKCC2) (Neuronal K-Cl cotransporter)
Gene: SLC12A5

Interactor 2: S12A6 (Q9UHW9)
Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)
Gene: SLC12A6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments unassigned3795
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains AA_permease~AA_permease, AA_permease~SLC12, SLC12~SLC12
Common GO terms GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0006884 - cell volume homeostasis
GO:0007268 - chemical synaptic transmission
GO:0015379 - potassium:chloride symporter activity
and 7 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1139
Hs

1 1150
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Last updated: 11Aug2025