Interactor 1: S12A5 (Q9H2X9)
Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (hKCC2) (Neuronal K-Cl cotransporter)
Gene: SLC12A5
Interactor 2: S12A4 (Q9UP95)
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1)
Gene: SLC12A4
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 1.00 | 0.712 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | unassigned3799, unassigned3795 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AA_permease~AA_permease, AA_permease~SLC12, SLC12~SLC12 |
| Common GO terms | GO:0005886 - plasma membrane GO:0006811 - monoatomic ion transport GO:0006884 - cell volume homeostasis GO:0007268 - chemical synaptic transmission GO:0015379 - potassium:chloride symporter activity and 5 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
