HitPredict

Interactor 1: RTN3 (O95197)
Reticulon-3 (Homolog of ASY protein) (HAP) (Neuroendocrine-specific protein-like 2) (NSP-like protein 2) (Neuroendocrine-specific protein-like II) (NSP-like protein II) (NSPLII)
Gene: RTN3

Interactor 2: LNP (Q9C0E8)
Endoplasmic reticulum junction formation protein lunapark (ER junction formation factor lunapark)
Gene: LNPK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0071786 - endoplasmic reticulum tubular network organization
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1032 Hs			1 428
+	Mm
		1186707 RTN3_MOUSE (1-1032): 2.67e-165: 513: 64.87		LNP_MOUSE (1-428): 0: 586: 84.42
+	Mm
		1186682 RTN1_MOUSE (433-1032): 5.12e-95: 320: 26.27		LNP_MOUSE (1-428): 0: 586: 84.42
+	Hs
		1319261 RTN4_HUMAN (64-1030): 9.26e-60: 225: 21.16		LNP_HUMAN (1-428): 0: 626: 100.00
+	Mm
		1186693 RTN4_MOUSE (47-1030): 1.43e-68: 252: 22.64		LNP_MOUSE (1-428): 0: 586: 84.42
+	Hs
		258969 RTN2_HUMAN (620-1024): 7.71e-50: 187: 22.49		LNP_HUMAN (1-428): 0: 626: 100.00
+	Hs
		1087793 RTN1_HUMAN (271-1028): 2.29e-45: 178: 22.73		LNP_HUMAN (1-428): 0: 626: 100.00