HitPredict

Interactor 1: TYDP2 (O95551)
Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (hTDP2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (ETS1-associated protein 2) (ETS1-associated protein II) (EAPII) (TRAF and TNF receptor-associated protein) (Tyrosyl-RNA phosphodiesterase) (VPg unlinkase)
Gene: TDP2

Interactor 2: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	14609633, 16524884
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Exo_endo_phos~Rad60-SLD
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0016604 - nuclear body GO:0016605 - PML body
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 362 Hs			1 101
+	Hs
		316318 TYDP2_HUMAN (1-362): 1.96e-137: 397: 100.00		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		316316 TYDP2_HUMAN (1-362): 1.96e-137: 397: 100.00		SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42