HitPredict

Interactor 1: DIRA3 (O95661)
GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI)
Gene: DIRAS3

Interactor 2: GDS1 (P52306)
Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein)
Gene: RAP1GDS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 607
+	Hs
		854121 DIRA2_HUMAN (33-229): 6.28e-86: 254: 47.98		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		854133 RAB1B_HUMAN (32-227): 2.55e-79: 238: 23.76		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		303756 DIRA1_HUMAN (37-229): 1.68e-49: 162: 46.63		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		854082 RAP1B_HUMAN (35-215): 1.46e-29: 110: 34.60		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		854088 RAP1A_HUMAN (35-203): 1.7e-28: 107: 35.67		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		854083 RAP2B_HUMAN (35-202): 3.17e-24: 96.7: 35.47		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		854120 RHES_HUMAN (38-202): 6.58e-23: 95.1: 31.03		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		854154 RAP2C_HUMAN (35-202): 2.03e-23: 94.4: 36.05		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		506444 RALB_HUMAN (38-196): 5.32e-21: 88.6: 31.25		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Xl
		292765 RALBA_XENLA (38-196): 4.14e-21: 89: 31.25		GDS1A_XENLA (1-607): 0: 899: 85.50
+	Dm
		51787 O96692_DROME (35-196): 1.73e-22: 92: 35.58		GDS1_DROME (62-536): 0: 540: 31.27
+	Dm
		51795 Q962I2_DROME (38-218): 3.16e-21: 89: 30.11		GDS1_DROME (62-536): 0: 540: 31.27