HitPredict

Interactor 1: HS74L (O95757)
Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Heat shock protein family H member 3) (Heat-shock protein family A member 4-like protein) (HSPA4-like protein) (Osmotic stress protein 94)
Gene: HSPA4L

Interactor 2: Q96BE0 (Q96BE0)
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)
Gene: Q96BE0

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	25036637
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP70~HSP70
Common GO terms	GO:0005524 - ATP binding GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 839 Hs			1 269
+	Hs
		320802 HS74L_HUMAN (1-839): 0: 1032: 100.00		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		320833 HS74L_HUMAN (1-839): 0: 1032: 100.00		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		713910 HSP74_HUMAN (1-839): 0: 931: 62.60		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58
+	Hs
		1120566 HS105_HUMAN (1-839): 0: 925: 58.24		Q53FA3_HUMAN (1-269): 1.68e-134: 395: 76.21
+	Hs
		714034 HS105_HUMAN (1-839): 0: 925: 58.24		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58
+	Hs
		503544 HSP74_HUMAN (1-839): 0: 931: 62.60		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		504490 HS105_HUMAN (1-839): 0: 925: 58.24		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		483777 HSP74_HUMAN (1-839): 0: 931: 62.60		HS71B_HUMAN (1-269): 2.24e-126: 374: 78.44
+	Hs
		714156 HSP74_HUMAN (1-839): 0: 931: 62.60		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		564020 HSP74_HUMAN (1-839): 0: 931: 62.60		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15
+	Hs
		871708 HS105_HUMAN (1-839): 0: 925: 58.24		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		714348 HSP74_HUMAN (1-839): 0: 931: 62.60		Q96BE0_HUMAN (1-269): 3.21e-125: 358: 100.00
+	Hs
		1267729 HS105_HUMAN (1-839): 0: 925: 58.24		Q96BE0_HUMAN (1-269): 3.21e-125: 358: 100.00
+	Hs
		503315 HSP7C_HUMAN (563-695): 1.3e-27: 121: 17.91		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		503543 HS71L_HUMAN (563-703): 9.9e-28: 121: 19.72		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Mm
		926115 HSP7C_MOUSE (563-695): 2.64e-27: 120: 17.16		HSP7C_MOUSE (1-269): 1.33e-130: 385: 99.63
+	Mm
		571859 HS71A_MOUSE (563-693): 3.25e-25: 113: 18.18		HS71B_MOUSE (1-269): 4.29e-130: 384: 77.70
+	Hs
		503752 HSP7C_HUMAN (563-695): 1.3e-27: 121: 17.91		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		503389 HSP7C_HUMAN (563-695): 1.3e-27: 121: 17.91		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15