HitPredict

Interactor 1: AP2A1 (O95782)
AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit)
Gene: AP2A1

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 977 Hs			1 779
+	Hs
		302207 AP2A2_HUMAN (1-977): 0: 832: 76.97		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		926010 AP2B1_HUMAN (34-972): 0: 676: 17.11		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1014080 AP1B1_HUMAN (34-972): 0: 668: 18.15		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		321570 AP2A1_HUMAN (1-977): 0: 904: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		212665 AP1G1_HUMAN (1-864): 0: 612: 23.74		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		321642 AP2A1_HUMAN (1-977): 0: 904: 100.00		PKHA2_HUMAN (1-258): 2.68e-38: 149: 15.90
+	Hs
		302172 AP2A2_HUMAN (1-977): 0: 832: 76.97		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1331635 AP4E1_HUMAN (2-586): 6.72e-153: 483: 24.79		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		150266 AP3D1_HUMAN (11-746): 3.68e-150: 476: 20.55		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		925912 AP2B1_HUMAN (34-972): 0: 676: 17.11		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1014032 AP1B1_HUMAN (34-972): 0: 668: 18.15		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		212634 AP1G1_HUMAN (1-864): 0: 612: 23.74		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		925943 AP2B1_HUMAN (34-972): 0: 676: 17.11		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		1014047 AP1B1_HUMAN (34-972): 0: 668: 18.15		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		212645 AP1G1_HUMAN (1-864): 0: 612: 23.74		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93