HitPredict

Interactor 1: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Interactor 2: DNJB1 (P25685)
DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1)
Gene: DNAJB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33957083, 35271311, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0051087 - protein-folding chaperone binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 340
+	Hs
		324095 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJB4_HUMAN (1-339): 1.15e-134: 388: 64.60
+	Hs
		279268 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJB5_HUMAN (1-339): 3.31e-126: 366: 59.71
+	Hs
		323608 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJA1_HUMAN (5-339): 2.97e-117: 346: 32.77
+	Hs
		243235 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJA2_HUMAN (2-339): 2.35e-115: 341: 33.24
+	Hs
		323926 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DNJA4_HUMAN (5-339): 1.42e-115: 341: 32.49
+	Hs
		324094 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DJB11_HUMAN (2-338): 8.5e-105: 313: 32.26
+	Dm
		1096123 Q9VUQ1_DROME (7-178): 4.48e-73: 223: 35.64		DNAJ1_DROME (1-339): 2.7e-118: 346: 51.32
+	Dm
		1096098 Q95RY2_DROME (25-178): 8.85e-65: 202: 36.15		DNAJ1_DROME (1-339): 2.7e-118: 346: 51.32